Year 2020 / Volume 112 / Number 11
Letter
Severe enterocolitis secondary to ipilimumab and nivolumab with an excellent response to a single dose of infliximab

889-890

DOI: 10.17235/reed.2020.6886/2020

Ana María Luque Carmona, Guillermo Ontanilla-Clavijo, Eduardo Leo Carnerero,

Abstract
Immunotherapy is gaining significance in the management of oncological disease. It has demonstrated high levels of efficacy, though it also has hitherto unknown side effects, such as colitis. We present the first case of immune checkpoint inhibitor colitis (nivolumab+ipilimumab) refractory to corticoids treated in our hospital.
Share Button
New comment
Comments
No comments for this article
References
1. Soularue E, Lepage P, Colombel JF et al. Enterocolitis due to immune checkpoint inhibitors: a systematic review. Gut. 2018 Nov;67(11):2056-2067.
2. Abdel-Wahab N, Shah M, Suarez-Almazor ME. Adverse Events Associated with Immune Checkpoint Blockade in Patients with Cancer: A Systematic Review of Case Reports. PLoS One. 2016 Jul 29;11(7):e0160221.
3. Yamauchi R, Araki T, Mitsuyama K et al. The characteristics of nivolumab-induced colitis: an evaluation of three cases and a literature review. BMC Gastroenterol. 2018 Aug 31;18(1):135.
4. Marthey L, Mateus C, Mussini C et al. Cancer Immunotherapy with Anti-CTLA-4 Monoclonal Antibodies Induces an Inflammatory Bowel Disease. J Crohns Colitis. 2016 Apr;10(4):395-401.
Related articles

Original

Megacolon in inflammatory bowel disease: response to infliximab

DOI: 10.17235/reed.2020.6394/2019

Citation tools
Luque Carmona A, Ontanilla-Clavijo G, Leo Carnerero E. Severe enterocolitis secondary to ipilimumab and nivolumab with an excellent response to a single dose of infliximab . 6886/2020


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1086 visits.
This article has been downloaded 194 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 18/01/2020

Accepted: 31/01/2020

Online First: 15/10/2020

Published: 10/11/2020

Article Online First time: 271 days

Article editing time: 297 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2024 y Creative Commons. The Spanish Journal of Gastroenterology