Year 2024 / Volume 116 / Number 4
Letter
Pseudoachalasia as a paraneoplastic event in a patient with Hodgkin’s disease

237-238

DOI: 10.17235/reed.2023.9921/2023

Raúl José Díaz Molina, Mariía José Bosque López, Sam Khorrami Minaei, Antonia Perelló Juan, Carmen Garrido Durán,

Abstract
Pseudoachalasia or secondary achalasia (5% of achalasias that are deemed primary achalasias) is an esophageal motor disorder with manometric criteria for achalasia, but it appears in the context of an underlying pathology that can be attributed to its origin. Usually appears in >60 years with rapid evolution of symptoms (<1 year). The main cause of pseudoachalasia is neoformative etiology, but there are others. Our patient started with rapid progression dysphagia and was diagnosed with type II achalasia within a Hodgkin's lymphoma. In the radiological-metabolic studies, disease involvement was ruled out as an extrinsic compression of the esophagogastric junction as well as signs of its activity at this level. Chemotherapy has not been shown to play a role in the development of this pathology. On the other hand, radiotherapy has been associated with an esophageal motor disorder, but, in our case, it was after its onset. Therefore, we propose that the mechanism of pseudoachalasia in our case is a paraneoplastic event. This hypothesis is related to other similar cases reported, and it reflects the importance of continuing to investigate this clinical condition that is indistinguishable by manometry from primary achalasia. In addition, it usually presents differential clinical characteristics whose early recognition has implications for the diagnostic, therapeutic, and prognostic management of the patient.
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References
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Citation tools
Díaz Molina R, Bosque López M, Khorrami Minaei S, Perelló Juan A, Garrido Durán C. Pseudoachalasia as a paraneoplastic event in a patient with Hodgkin’s disease. 9921/2023


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Publication history

Received: 29/08/2023

Accepted: 12/09/2023

Online First: 29/09/2023

Published: 09/04/2024

Article Online First time: 31 days

Article editing time: 224 days


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