Year 2024 / Volume 116 / Number 4
Letter
Pseudoachalasia as a paraneoplastic event in a patient with Hodgkin’s disease

237-238

DOI: 10.17235/reed.2023.9921/2023

Raúl José Díaz Molina, Mariía José Bosque López, Sam Khorrami Minaei, Antonia Perelló Juan, Carmen Garrido Durán,

Abstract
Pseudoachalasia or secondary achalasia (5% of achalasias that are deemed primary achalasias) is an esophageal motor disorder with manometric criteria for achalasia, but it appears in the context of an underlying pathology that can be attributed to its origin. Usually appears in >60 years with rapid evolution of symptoms (<1 year). The main cause of pseudoachalasia is neoformative etiology, but there are others. Our patient started with rapid progression dysphagia and was diagnosed with type II achalasia within a Hodgkin's lymphoma. In the radiological-metabolic studies, disease involvement was ruled out as an extrinsic compression of the esophagogastric junction as well as signs of its activity at this level. Chemotherapy has not been shown to play a role in the development of this pathology. On the other hand, radiotherapy has been associated with an esophageal motor disorder, but, in our case, it was after its onset. Therefore, we propose that the mechanism of pseudoachalasia in our case is a paraneoplastic event. This hypothesis is related to other similar cases reported, and it reflects the importance of continuing to investigate this clinical condition that is indistinguishable by manometry from primary achalasia. In addition, it usually presents differential clinical characteristics whose early recognition has implications for the diagnostic, therapeutic, and prognostic management of the patient.
Share Button
New comment
Comments
No comments for this article
References
1. Schizas D, Theochari NA, Katsaros I, Mylonas KS, Triantafyllou T, Michalinos A, Kamberoglou D, Tsekrekos A, Rouvelas I. Pseudoachalasia: a systematic review of the literature. Esophagus. 2020 Jul;17(3):216-222. doi: 10.1007/s10388-020-00720-1.
2. Haj Ali SN, Nguyen NQ, Abu Sneineh AT. Pseudoachalasia: a diagnostic challenge. When to consider and how to manage? Scand J Gastroenterol. 2021 Jul;56(7):747-752. doi: 10.1080/00365521.2021.1925957.
3. Katzka DA, Farrugia G, Arora AS. Achalasia secondary to neoplasia: a disease with a changing differential diagnosis. Dis Esophagus. 2012 May;25(4):331-6. doi: 10.1111/j.1442-2050.2011.01266.x.
4. Vitton V, Andrianjafy C, Luciano L, Gonzalez JM, Padovani L. Radio-induced esophageal motility disorders: An unrecognized diagnosis. Cancer Radiother. 2021 May;25(3):249-253. doi: 10.1016/j.canrad.2020.09.006.
5. Peeples WJ, El-Mahdi AM, Rosato FE. Achalasia of the esophagus associated with Hodgkin disease. J Surg Oncol. 1979;11(3):213-6. doi: 10.1002/jso.2930110305.
Related articles

Letter

When eating becomes a real nightmare

DOI: 10.17235/reed.2023.10025/2023

Letter

Drug-induced sudden dysphagia

DOI: 10.17235/reed.2023.9989/2023

Digestive Diseases Image

Dysphagia secondary to neuroendocrine carcinoma: a rare esophageal tumor

DOI: 10.17235/reed.2023.9951/2023

Digestive Diseases Image

Solid food dysphagia caused by aortic arch malformation compressing the esophagus

DOI: 10.17235/reed.2023.9923/2023

Letter

Esophageal necrosis secondary to thoracic aortic aneurysm

DOI: 10.17235/reed.2023.9580/2023

Digestive Diseases Image

Esophageal lichen planus: an unusual case of dysphagia

DOI: 10.17235/reed.2023.9572/2023

Letter

Large symptomatic esophageal diverticulum

DOI: 10.17235/reed.2023.9518/2023

Digestive Diseases Image

A giant cause of recurrent fever

DOI: 10.17235/reed.2022.9340/2022

Letter

Eagle’s syndrome as a cause of oropharyngeal dysphagia

DOI: 10.17235/reed.2022.9295/2022

Letter

Familial dysphagia: eosinophilic esophagitis

DOI: 10.17235/reed.2019.6610/2019

Letter

Esophageal lichen planus: a rare cause of dysphagia

DOI: 10.17235/reed.2019.6064/2018

Letter

An unexpected cause of dysphagia: pleural mesothelioma

DOI: 10.17235/reed.2019.6024/2018

Letter

Dysphagia lusoria: uncommon cause of dysphagia in children

DOI: 10.17235/reed.2018.5664/2018

Digestive Diseases Image

Dysphagia lusoria: a little-known cause of dysphagia

DOI: 10.17235/reed.2018.5385/2017

Case Report

Peroral endoscopic myotomy in pediatric jackhammer esophagus

DOI: 10.17235/reed.2018.5090/2017

Letter to the Editor

Utility of surgical myotomy in the dysphagia due to oculopharyngeal dystrophy

DOI: 10.17235/reed.2016.4266/2016

Citation tools
Díaz Molina R, Bosque López M, Khorrami Minaei S, Perelló Juan A, Garrido Durán C. Pseudoachalasia as a paraneoplastic event in a patient with Hodgkin’s disease. 9921/2023


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1390 visits.
This article has been downloaded 57 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 29/08/2023

Accepted: 12/09/2023

Online First: 29/09/2023

Published: 09/04/2024

Article Online First time: 31 days

Article editing time: 224 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2024 y Creative Commons. The Spanish Journal of Gastroenterology