Year 2024 / Volume 116 / Number 8
Letter
Drug-induced sudden dysphagia

459-460

DOI: 10.17235/reed.2023.9989/2023

Celia Gutiérrez Holanda, Fernando Berdugo Hurtado, Pilar Martínez Tirado,

Abstract
Doxycycline is a bacteriostatic antibiotic of the tetracycline group widely indicated in the treatment of numerous infections (skin, soft tissues...). Given its acid nature, doxycycline is able to potentially generate mucous damage acting as a caustic; therefore, when the capsule of doxycycline (high concentrated substance) is taken inappropriately (with a small quantity of liquid or just before laying down) and remains for a longer time in contact with the esophagus, doxycycline may cause esophagitis-type lesions and ulcerations.
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References
1. M. Alonso Fernández Equipo de Atención Primaria de La Ería. Oviedo. Principado de Asturias. España. Úlcera esofágica y doxiciclina. Elsevier Atención Primaria. Vol. 36. Núm. 4. Páginas 224. Septiembre 2005. DOI: 10.1157/13078599.
2. D. Pérez-de Luque, J.A. Peña-Ojeda, A.M. Monrobel-Lacho. Úlcera secundaria a toma de doxiciclina. RAPD Online. Vol. 34. Núm. 2. Marzo – abril 2011.
3. AEMPS. Circular 11/2000: información que se debe incorporar en las Fichas Técnicas y Prospectos de las especialidades farmacéuticas con doxiciclina (sola o en asociación) formuladas como formas sólidas de administración oral.
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Gutiérrez Holanda C, Berdugo Hurtado F, Martínez Tirado P. Drug-induced sudden dysphagia. 9989/2023


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Publication history

Received: 29/09/2023

Accepted: 05/10/2023

Online First: 26/10/2023

Published: 01/08/2024

Article Online First time: 27 days

Article editing time: 307 days


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