Year 2024 / Volume 116 / Number 12
Letter
Liver enzyme alteration in response to dengue virus

731

DOI: 10.17235/reed.2023.10102/2023

Marta Álvarez-García, Lola Otegui, Adriana Ortega Larrodé, Rocío Calvo Hernández,

Abstract
Infectious diseases are extremely important in the global health landscape, specifically dengue and its severe forms. Clinical characterization is very variable due to the wide spectrum of manifestations the virus induces. Dengue is a viral infection caused by the dengue virus and is transmitted to humans by mosquitos of the Aedes family. Dengue is the most important arthropod-borne disease and if symptoms occur, could appear suddenly, characterized by biphasic fever, headache, retroocular pain, pain in various parts of the body, prostration and rash. It has also been described that the Dengue virus can also cause liver dysfunction that could vary from mild injury to severe hepatocyte injury, commonly in tropical and subtropical climates. We report the case of a 24-year-old female who came to the emergency room due to fever and myalgia, in the context of a recent trip to Cuba. Physical examination included positive tourniquet test and laboratory findings showed anaemia and thrombocytopenia, as well as elevated transaminase levels. Serologic tests for dengue virus are requested and a positive result of specific antibodies-IgM classified the patient as presumptive being necessary to confirm authorities the outbreak and explain the patient it requires a close monitoring. Abdominal ultrasound showed mild splenomegaly. Because of progressive analytical normalization, the patient asked for outpatient care.
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References
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Álvarez-García M, Otegui L, Ortega Larrodé A, Calvo Hernández R. Liver enzyme alteration in response to dengue virus . 10102/2023


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Publication history

Received: 20/11/2023

Accepted: 23/11/2023

Online First: 14/12/2023

Published: 13/12/2024

Article Online First time: 24 days

Article editing time: 389 days


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