Year 2020 / Volume 112 / Number 1
Original
Clinical validation of Endofaster® for a rapid diagnosis of Helicobacter pylori infection

23-26

DOI: 10.17235/reed.2019.6441/2019

Eugenia Sánchez Rodríguez, Rubén Sánchez Aldehuelo, Raquel Ríos León, Rosa María Martín Mateos, Ana García García de Paredes, Carlos Martín de Argila, Alejandra Caminoa, Agustín Albillos, Enrique Vázquez-Sequeiros,

Abstract
Background: this study aimed to evaluate the diagnostic accuracy of the Endofaster® for the detection of Helicobacter pylori. Methods: during upper gastrointestinal endoscopy, gastric juice was aspirated to perform an analysis using the Endofaster®. This test was considered as positive when the ammonium concentration was > 67 ppm, negative when < 57 ppm and weakly positive between 57 and 67. Biopsy specimens were also taken as the gold standard. Results: among the 86 patients enrolled in the study, the Endofaster® result was positive in 23.7%, negative in 54.7% and weakly positive in 11.6%, whereas infection was detected via histology in 38.4% of patients. The accuracy was 81.4%, with a Kappa value of 0.57. Conclusions: the Endofaster® could be useful to perform a rapid diagnosis of Helicobacter pylori infection (area under the curve = 0.81).
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Sánchez Rodríguez E, Sánchez Aldehuelo R, Ríos León R, Martín Mateos R, García García de Paredes A, Martín de Argila C, et all. Clinical validation of Endofaster® for a rapid diagnosis of Helicobacter pylori infection. 6441/2019


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Publication history

Received: 12/06/2019

Accepted: 02/08/2019

Online First: 22/11/2019

Published: 10/01/2020

Article revision time: 43 days

Article Online First time: 163 days

Article editing time: 212 days


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