Year 2022 / Volume 114 / Number 11
Letter
Ectopic ACTH syndrome in a patient with Crohn’s disease

690-691

DOI: 10.17235/reed.2022.8825/2022

Alberto Pérez Ramírez, Antonio Moreno Loro, Javier Mohigefer Barrera, José Manuel Herrera Justiniano,

Abstract
We present the case of a 62-year-old man with Crohn's disease who consulted for abdominal pain and lower limbs edema. The patient developed Cushing's syndrome due to ectopic secretion of ACTH. Diagnostic imaging tests showed multiple metastatic liver lesions and asymmetric thickening of the ileum, that was suspected as the primary tumor. This tumor produced destabilizing gastrointestinal bleeding and an urgent surgical resection was performed. The histopathological study of the resection specimen confirmed a grade 3 neuroendocrine tumor.
Share Button
New comment
Comments
No comments for this article
References
1.Pellino G, Marcellinaro R, Candilio G, De Fatico GS, Guadagno E, Campione S, Santangelo G, Reginelli A, Sciaudone G, Riegler G, Canonico S, Selvaggi F. The experience of a referral centre and literature overview of GIST and carcinoid tumours in inflammatory bowel diseases. Int J Surg. 2016 Apr;28 Suppl 1:S133-41. doi: 10.1016/j.ijsu.2015.12.051. Epub 2015 Dec 18. PMID: 26708852.
2. Pavel M, Öberg K, Falconi M, Krenning EP, Sundin A, Perren A, Berruti A; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org. Gastroenteropancreatic neuroendocrine neoplasms: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2020 Jul;31(7):844-860. doi: 10.1016/j.annonc.2020.03.304. Epub 2020 Apr 6. PMID: 32272208.
3. Mineur L, Boustany R, Vazquez L. Paraneoplastic Cushing Syndrome in Gastrointestinal Neuroendocrine Tumour. Case Rep Oncol. 2021 Sep 23;14(3):1407-1413. doi: 10.1159/000518316. PMID: 34720949; PMCID: PMC8525292.
4. Eriksson B, Klöppel G, Krenning E, Ahlman H, Plöckinger U, Wiedenmann B, et al. Consensus guidelines for the management of patients with digestive neuroendocrine tumors well-differentiated jejunal-ileal tumor/carcinoma. Neuroendocrinol. 2008;87((1)):8–19.
5. Shah CP, Mramba LK, Bishnoi R, Unnikrishnan A, Duff JM, Chandana SR, et al. Survival trends of metastatic small intestinal neuroendocrine tumor: a population-based analysid of SEER database. J Gastrointest Oncol. 2019;10((5)):869–77.
Related articles

Letter

Surgical indication of type I gastric neuroendocrine tumors

DOI: 10.17235/reed.2023.9681/2023

Letter

Carcinoid syndrome and somatostatin analogues

DOI: 10.17235/reed.2023.9525/2023

Letter

Isolated Jejunal Crohn's Disease: a challenging diagnosis

DOI: 10.17235/reed.2022.9423/2022

Letter

Comb sign in Crohn’s disease

DOI: 10.17235/reed.2022.9132/2022

Letter

Pulmonary nodules in a patient with Crohn’s disease

DOI: 10.17235/reed.2022.8499/2021

Digestive Diseases Image

Endoscopic resection of a duodenal neuroendocrine tumor

DOI: 10.17235/reed.2021.8232/2021

Letter

Adenocarcinoma of the small intestine in Crohn's disease

DOI: 10.17235/reed.2021.8050/2021

Digestive Diseases Image

A rare cause of extrahepatic biliary tract stricture: a neuroendocrine carcinoma

DOI: 10.17235/reed.2020.6491/2019

Letter

Klatskin-mimicking neuroendocrine tumor

DOI: 10.17235/reed.2019.6382/2019

Letter to the Editor

Author´s reply: Cystic pancreatic neuroendocrine tumors. A diagnostic challenge

DOI: 10.17235/reed.2018.5415/2017

Letter to the Editor

A case of a mixed adenoneuroendocrine tumor of the colon

DOI: 10.17235/reed.2017.5008/2017

Letter to the Editor

Neuroendocrine tumors of the pancreas: keys issues in dealing with heterogeneity

DOI: 10.17235/reed.2017.4997/2017

Letter to the Editor

Pancreatic neuroendocrine tumors. Prognostic factors

DOI: 10.17235/reed.2017.5109/2017

Letter to the Editor

Pancreatic neuroendocrine tumors

DOI: 10.17235/reed.2017.4725/2016

Editorial

Pancreas neuroendocrine tumors - not so rare or benign

DOI: 10.17235/reed.2016.4672/2016

Letter to the Editor

Unusual presentation of obstructive jaundice

DOI: 10.17235/reed.2017.4501/2016

Letter to the Editor

Gastric neuroendocrine tumor presenting with gastrointestinal bleeding

DOI: 10.17235/reed.2015.3998/2015

Citation tools
Pérez Ramírez A, Moreno Loro A, Mohigefer Barrera J, Herrera Justiniano J. Ectopic ACTH syndrome in a patient with Crohn’s disease. 8825/2022


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1754 visits.
This article has been downloaded 77 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 29/03/2022

Accepted: 05/04/2022

Online First: 12/05/2022

Published: 07/11/2022

Article Online First time: 44 days

Article editing time: 223 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology