Year 2019 / Volume 111 / Number 6
Letter
A rare lymphoproliferative disorder associated with immunomodulating therapy in Crohn’s disease

491

DOI: 10.17235/reed.2019.5990/2018

Eduardo López Fernández, María Curieses Luengo, Pilar Varela Trastoy,

Abstract
Lymphomatoid granulomatosis is a rare lymphoproliferative disorder associated with immunosuppressive therapy in inflammatory bowel disease. We present the case of a patient with Crohn's disease and treated azathioprine that develops lymphomatoid granulomatosis, as well as its diagnostic process and the chosen treatment. Lymphomatoid granulomatosis is a serious disease barely described and whose suspicion is essential for its prognosis.
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References
(1) Carolyn D. Rysgaard, Mary Seabury Stone. Lymphomatoid granulomatosis presenting with cutaneous, a case report and review of the literature. Cutan Pathol 2015; 42: 188–193.
(2) Anna-Luise A. K. et al. Lymphomatoid Granulomatosis insights gained over 4 decades. Am J Surg Pathol 2010; 34: e35–e48.
(3) Thomas V. Colby. Current histological diagnosis of lymphomatoid granulomatosis. Modern Pathology 2012; 25: S39–S42.
(4) William Connors, Cameron Griffiths, Jay Patel and Paul J Belletrutti. Lymphomatoid granulomatosis associated with azathioprinetherapy in Crohn disease. BMC Gastroenterology 2014; 14:127.
(5) Grosse Alexandra1 & Grosse Claudia. Lymphomatoid granulomatosis mimicking cancer and sarcoidosis. Ann Hematol. 2018 Oct 5. doi: 10.1007/s00277-018-3505-4.
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López Fernández E, Curieses Luengo M, Varela Trastoy P. A rare lymphoproliferative disorder associated with immunomodulating therapy in Crohn’s disease. 5990/2018


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Publication history

Received: 19/10/2018

Accepted: 30/10/2018

Online First: 25/04/2019

Published: 07/06/2019

Article Online First time: 188 days

Article editing time: 231 days


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