Year 2016 / Volume 108 / Number 9
Case Report
Severe ischemic colitis following olanzapine use - A case report

595-598

DOI: 10.17235/reed.2016.3944/2015

Samuel R. Fernandes, Rosa Alves, Luís Araújo Correia, Ana Rita Gonçalves, João Malaquias, Emilia Oliveira, José Velosa,

Abstract
Ischemic colitis is the most common subtype of intestinal ischemia usually resulting from vasospasm, vessel occlusion or mesenteric hypoperfusion. Neuroleptics have seldom been linked to ischemic colitis by blocking peripheral anticholinergic and antiserotonergic receptors inducing severe gastrointestinal paresis. We report a young patient with severe ischemic colitis requiring surgery due to necrosis of the bowel. After exclusion of other potential causes, olanzapine was admitted as the cause of ischemia. Clinicians should be aware of how to recognize and treat the potentially life-threatening effects of neuroleptics.
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Fernandes S, Alves R, Araújo Correia L, Rita Gonçalves A, Malaquias J, Oliveira E, et all. Severe ischemic colitis following olanzapine use - A case report. 3944/2015


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Publication history

Received: 25/07/2015

Accepted: 07/08/2015

Online First: 20/01/2016

Published: 06/09/2016

Article revision time: 10 days

Article Online First time: 179 days

Article editing time: 409 days


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