Year 2024 / Volume 116 / Number 12
Letter
Retiform purpura, a rare chemoembolization adverse outcome

711

DOI: 10.17235/reed.2023.10063/2023

Sandra Borrego Rivas, Alia Martín Izquierdo, Raisa Quiñones Castro, Víctor Onecha Vallejo, Noanca Alonso Fernández, Laura Alcoba Vega, Isabel González Puente, Francisco Jorquera Plaza,

Abstract
Transcatheter arterial chemoembolization (TACE) is currently one of the standards of treatment for unresectable hepatocellular carcinoma in the intermediate stage. It is a minimally invasive procedure whose adverse outcomes are well documented. Among those considered uncommon, we find skin outcomes. We report a 73-year-old man who, after undergoing TACE, develops a necrotic retiform purpura due to occlusion of the microcirculation of the cutaneous and subcutaneous tissue caused by migration of doxorubicin spheres. This is an infrequent complication, which presents with pain in the affected area. Its management is based on prevention, which is the reason why awareness of this condition is so important.
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References
1. Kuan A, Khoo L, Yang SS, Chia HY, Lee JSS. Retiform Purpura as a Complication of Microsphere Emboli Following Transarterial Chemoembolization for Primary Hepatocellular Carcinoma: A Case Report and Literature Review. The American Journal of Dermatopathology. julio de 2020;42(7):e108-10.
2. Hansen T, Olsen K, White K, Keller J. Retiform Purpura After Transcatheter Arterial Chemoembolization: A Case Report. The American Journal of Dermatopathology. febrero de 2018;40(2):e25-7.
3. Li Z, Cai Z, Dai S, Deng H, Li Z, Ji F. Cutaneous Necrosis Associated with Transcatheter Arterial Chemoembolization of the Intercostal Artery. Journal of Vascular and Interventional Radiology. julio de 2014;25(7):1141-1148.e1.
4. Wang, D.S. et al. (2013a) ‘Prophylactic topically applied ice to prevent cutaneous complications of nontarget chemoembolization and Radioembolization’, Journal of Vascular and Interventional Radiology, 24(4), pp. 596–600.
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Borrego Rivas S, Martín Izquierdo A, Quiñones Castro R, Onecha Vallejo V, Alonso Fernández N, Alcoba Vega L, et all. Retiform purpura, a rare chemoembolization adverse outcome. 10063/2023


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Publication history

Received: 05/11/2023

Accepted: 15/11/2023

Online First: 30/11/2023

Published: 13/12/2024

Article Online First time: 25 days

Article editing time: 404 days


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