Year 2022 / Volume 114 / Number 6
Letter
Recidivant odynophagia secondary to persistent esophageal candidiasis in an immunocompetent patient: the importance of brush cytology

359-360

DOI: 10.17235/reed.2022.8376/2021

Concepción López Peña, Andrés Barrientos Delgado, Miguel Soler Góngora,

Abstract
We present the case of a 53-year-old smoker woman without any relevant medical history who was attended as an outpatient due to several-month persistent odynophagia. An upper gastrointestinal endoscopy was performed, showing white cotton-like plaques throughout the esophagus, suggestive of candidiasis. An esophageal brushing plus biopsy sampling were done, empirically prescribing oral fluconazole for 21 days. A viral serology was also requested, with negative results. Clinical improvement was present until the suspension of antifungal treatment, with an odynophagia relapse afterwards. Cultures were positive for C.albicans sensitive to fluconazole.
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References
1. Barnali Kakati et al., Fluconazole Resistant Candida Oesophagitis in Immunocompetent Patients. Journal of Clinical and Diagnostic Research. 2015 Dec, Vol-9(12).
2. Zhan SK, Wu XQ, Zheng FP. Clinical Characteristics and Manifestations of Fungal Esophagitis: A Single-Center Experience in South China. Gastroenterol Res Pract. 2021;2021:8869494.
3. Wilson A, Delport J, Ponich T. Candida glabrata Esophagitis: Are We Seeing the Emergence of a New Azole-Resistant Pathogen? Int J Microbiol. 2014;2014:371631.
4. Talukdar A, Barman R, Sarma A, et al. Fungal profile and antifungal susceptibility pattern of candidiasis in esophageal cancer patients. J Can Res Ther 2020;16, Suppl S1:209-12
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Citation tools
López Peña C, Barrientos Delgado A, Soler Góngora M. Recidivant odynophagia secondary to persistent esophageal candidiasis in an immunocompetent patient: the importance of brush cytology. 8376/2021


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Publication history

Received: 07/10/2021

Accepted: 12/01/2022

Online First: 26/01/2022

Published: 07/06/2022

Article Online First time: 111 days

Article editing time: 243 days


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