Year 2016 / Volume 108 / Number 10
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Pseudomelanosis duodeni: is there a common denominator?

658-659

Rosa Coelho, Armando Ribeiro, Roberto Silva, Elisabete Rios, Marco Silva, Guilherme Macedo,

Abstract
A 76-year-old female patient with a past medical history of diabetes mellitus, stage 3 chronic renal failure and iron deficiency anemia was referred for esophagogastroduodenoscopy (EGD) for evaluation of solid food dysphagia. She had been on oral therapy with ferrous sulfate for several years. Besides a Schatzki’s ring the EGD revealed a duodenal mucosa with black-speckled pigmentation. Biopsies were performed and disclosed the deposition of brown (hemosiderin) pigment within macrophages in the lamina propria of normal villi. This endoscopic appearance is called pseudomelanosis duodeni (PD).
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References
1- Cantu JA, Adler DG. Pseudomelanosis duodeni. Endoscopy. 2005;37:789
2- Castellano G, Canga F, Lopez I, et al. Pseudomelanosis of the duodenum. Endoscopic, histologic, and ultrastructural study of a case. J Clin Gastroenterol. 1988;10:150-4.
3- Magalhães Costa MH, Fernandes Pegado M, Vargas C, et al. Pseudomelanosis duodeni associated with chronic renal failure. World J Gastroenterol. 2012;18:1414–6.
4- Kim SY, Choung RS, Kwon BS, et al. Small bowel pseudomelanosis associated with oral iron therapy. J Korean Med Sci. 2013;28:1103-6.
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Coelho R, Ribeiro A, Silva R, Rios E, Silva M, Macedo G, et all. Pseudomelanosis duodeni: is there a common denominator? . 3986/2015


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Publication history

Received: 26/08/2015

Accepted: 13/09/2015

Published: 30/09/2016

Article revision time: 13 days

Article editing time: 401 days


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