Year 2023 / Volume 115 / Number 1
Letter
Multiple papillary intralymphatic angioendotheliomas in the spleen

46-47

DOI: 10.17235/reed.2022.8966/2022

Liping Wang, Qinglin Yang, Huihui Zhou, Jun Li,

Abstract
A 18-year-old man presented with multiple asymptomatic masses in the spleen that had been detected on ultrasonography performed during a physical screening. He had no history of tuberculosis, and was otherwise well. Abdominal MR demonstrated multiple masses with internal stellate scars, which appeared as marked hypointensity on T2WI and contrast-enhanced MR. Most lesions showed inhomogeneous enhancement. The capsular enhancement was also revealed at delay phase. The patient underwent laparoscopic splenectomy. Pathological examination indicated papillary intralymphatic angioendothelioma (PILA), with the following immunohistochemistry results: CK (-), CR (-), ERG (+), CD34 (+), CD31 (+), D2-40 (+), Ki67 (3%+). The patient was feeling well at 6 months of follow-up.
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References
1.Kaplan GO, Menku Özdemir FD, Orhan D, et al. Papillary intralymphatic angioendothelioma: An extremely rare tumor. Jt Dis Relat Surg. 2021;32(1):245-248.
2.Rodgers B, Zeim S, Crawford B, et al. Splenic papillary angioendothelioma in a 6-year-old girl. J Pediatr Hematol Oncol. 2007;29(12):808-810.
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Wang L, Yang Q, Zhou H, Li J. Multiple papillary intralymphatic angioendotheliomas in the spleen. 8966/2022


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Publication history

Received: 28/05/2022

Accepted: 01/06/2022

Online First: 15/06/2022

Published: 12/01/2023

Article Online First time: 18 days

Article editing time: 229 days


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