Year 2021 / Volume 113 / Number 3
Letter
Intestinal burying of the jejunal-tube of a PEG-J levodopa-carbidopa release system for Parkinson’s disease. Successful endoscopic management

226-227

DOI: 10.17235/reed.2020.7180/2020

Óscar Moralejo Lozano, Adrián Joaquín Barrajón Masa, Michel Colmenares Bulgheroni,

Abstract
Levodopa-carbidopa intestinal gel (LCIG) continuous infusion into the jejunum through a percutaneous endoscopic gastrostomy with a jejunal extension (PEG-J) is an alternative therapy for Parkinson’s disease (PD) patients, with a very poor control of their symptoms on regular oral medications (Hoehn-Yahr stage IV). Around 62.2 % of patients present procedure and device-related adverse effects (AE), with an 8.2 % rate of mayor complications.
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References
1. Garrido Durán C, Khorrami Minaei S, Sendra Rumbeu P, et al. Aspectos endoscópicos del tratamiento de la enfermedad de Parkinson avanzada con levodopa/carbidopa intraduodenal. Rev Esp Enferm Dig 2019; 111(11):828-832. DOI: 10.17235/reed.2019.6311/2019
2. Olivares A, Collado D, Muñoz-Navas M, et al. Complications of percutaneous endoscopic gastrostomy-jejunostomy for levodopa/carbidopa infusion in advanced Parkinson's disease. Gastroenterology Insights. 2012;4:13–15. DOI: 10.4081/gi.2012.e4
3. Bianco G, Vuolo G, Ulivelli M, et al. A clinically silent, but severe, duodenal complication of duodopa infusion. J Neurol Neurosurg Psychiatry. 2012;83:668–670. DOI: 10.1136/jnnp-2011-301984
4. Russo P, Costa M, Silva M, et al. Fistulization of J-PEG Jejunal Tube into the Colon in a Patient Treated with Duodopa® Infusion: A Case Report. GE Port J Gastroenterol. 2017;24(3):147–150. DOI:10.1159/000452694
5. Marano M, Pizzicannella M, di Biase L, et al. Jejunal pulling syndrome: a peculiar LCIG complication. Parkinsonism Relat Disord. 2018;52:113–114. DOI: 10.1016/j.parkreldis.2018.03.016
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Moralejo Lozano Ó, Barrajón Masa A, Colmenares Bulgheroni M. Intestinal burying of the jejunal-tube of a PEG-J levodopa-carbidopa release system for Parkinson’s disease. Successful endoscopic management. 7180/2020


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Publication history

Received: 23/04/2020

Accepted: 02/05/2020

Online First: 19/11/2020

Published: 08/03/2021

Article Online First time: 210 days

Article editing time: 319 days


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