Year 2025 / Volume 117 / Number 1
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Digestive pseudopolyposis as a form of presentation of digestive metastases of primary gastric leiomyosarcoma

58-59

DOI: 10.17235/reed.2023.9626/2023

Olga Ortega Lobete, Alberto Pérez Garvin, Isabel Payeras Otero, Óscar Nogales Rincón,

Abstract
A 71-year-old male was diagnosed with gastric leiomyosarcoma in 2020 after biopsies of an ulcerated gastric lesion. Despite oncological treatment, he presented bone, liver and lung progression. Fourth line treatment with Pazopanib was started in 2022 with no evidence of intestinal or peritoneal metastases. He was attended in the Emergency Department in February 2023 due to symptoms of gastrointestinal bleeding with clinical and analytical repercussion with hemoglobin 5.8g/dl. Initially he presented hematemesis and subsequently hematochezia. An upper and lower endoscopic study was performed, revealing multiple sessile polypoid lesions with an irregular mucosal pattern of between 5-30 mm distributed throughout all explored sections at the gastric, duodenal and colic mucosal; some of them ulcerated with fibrin deposits on the surface and signs of recent hemostasis. The histological study demonstrated infiltration by spindle-shaped mesenchymal cells with atypical nuclei, a Ki-67 proliferation index >80%, and an immunohistochemical profile consistent with digestive metastases of primary gastric leiomyosarcoma. CT scan was performed confirming tumor progression with pulmonary, digestive, hepatic, bone, muscle and peritoneal dissemination of gastric leiomyosarcoma.
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Ortega Lobete O, Pérez Garvin A, Payeras Otero I, Nogales Rincón Ó. Digestive pseudopolyposis as a form of presentation of digestive metastases of primary gastric leiomyosarcoma . 9626/2023


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Publication history

Received: 28/03/2023

Accepted: 05/04/2023

Online First: 12/05/2023

Published: 10/01/2025

Article Online First time: 45 days

Article editing time: 654 days


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