Year 2021 / Volume 113 / Number 1
Letter
Bortezomib-induced acute pancreatitis, an uncommon adverse event

77

DOI: 10.17235/reed.2020.7120/2020

Eduardo Junquera Alonso, Lucía Seoane Blanco, Francisco Xavier Cano Calderero,

Abstract
Acute pancreatitis is one of the main reasons for hospitalization, with an increasing incidence and associated non-negligible morbidity and mortality. Its most common causes are alcohol and gallstones, and medications are a rare cause. The pathogenesis of acute drug pancreatitis is not yet known exactly and the diagnosis is based on the evident temporal relationship, having excluded the rest of the possible known causes of acute pancreatitis. We present the case of a 71-year-old patient diagnosed with IgG multiple myeloma treated with the Daratumumab, Bortezomib and Dexamethasone regimen. After Bortezomib administration, he developed epigastric pain and elevated pancreatic enzymes in the range of acute pancreatitis. After ruling out common causes, the diagnosis of acute pancreatitis caused by Bortezomib was reached, which presents a favorable rapid evolution after its elimination.
Share Button
New comment
Comments
No comments for this article
References
Talamo G, Sivik J, Pandey MK, et al. Bortezomib-induced acute pancreatitis: Case report and review of the literature. J Oncol Pharm Pract. 2016 Apr;22(2):332-4.
Wang HH, Tsui J, Wang XY, et al. Bortezomib-induced acute pancreatitis in a patient with multiple myeloma. Leuk Lymphoma. 2014 Jun;55(6):1404-5.
Gupta H, Bansal R, Khanna S, et al. An unusual complication of bortezomib therapy: Acute pancreatitis. Indian J Nephrol. 2014 Mar;24(2):135-6.
García MC, Moreno A, Rosales JM, et al. Caso de pancreatitis aguda tóxica por infusiones de cola de caballo. Rev Esp Enferm Dig 2017;109(4):301-304.
Related articles

Editorial

Etiological diagnosis of recurrent acute pancreatitis

DOI: 10.17235/reed.2024.10404/2024

Letter

Anemia can predict organ failure in acute pancreatitis

DOI: 10.17235/reed.2023.9700/2023

Editorial

Acute pancreatitis: an opportunity for gastroenterology hospitalists?

DOI: 10.17235/reed.2022.8573/2022

Digestive Diseases Image

Endoscopic necrosectomy – when the gastroenterologist faces his greatest nightmare.

DOI: 10.17235/reed.2021.8403/2021

Digestive Diseases Image

Wunderlich syndrome secondary to severe acute pancreatitis

DOI: 10.17235/reed.2021.8184/2021

Letter

Acute pancreatitis related to SARS-CoV-2 infection. Disclaimer

DOI: 10.17235/reed.2021.7853/2021

Letter

Pancreatic injury and acute pancreatitis in COVID-19 patients

DOI: 10.17235/reed.2021.7807/2021

Letter

Pancreatic injury in COVID-19: pathogenesis and challenges

DOI: 10.17235/reed.2020.7541/2020

Letter

SARS-CoV-2 and acute pancreatitis: a new etiological agent?

DOI: 10.17235/reed.2020.7481/2020

Letter

Acute pancreatitis associated with levofloxacin

DOI: 10.17235/reed.2020.6652/2019

Digestive Diseases Image

Endoscopic therapy in disconnected duct syndrome: re-connecting the duct

DOI: 10.17235/reed.2020.6650/2019

Digestive Diseases Image

Colon perforation due to fistulization of a pancreatic pseudocyst

DOI: 10.17235/reed.2018.5884/2018

Digestive Diseases Image

A rare case of acute obstructive suppurative pancreatic ductitis associated with ERCP

DOI: 10.17235/reed.2018.5756/2018

Letter to the Editor

A patient with Castleman’s disease mimicking acute pancreatitis

DOI: 10.17235/reed.2017.5120/2017

Letter to the Editor

Abdominal compartment syndrome secondary to acute necrotizing pancreatitis

DOI: 10.17235/reed.2017.4810/2016

Letter to the Editor

Genetics in idiopathic pancreatitis and acute recurrent pancreatitis

DOI: 10.17235/reed.2017.4632/2016

Letter to the Editor

Intramural gastric hematoma in the context of an acute pancreatitis

DOI: 10.17235/reed.2017.4494/2016

Case Report

Acute hemorrhagic necrotizing pancreatitis in falciparum malaria

DOI: 10.17235/reed.2015.3768/2015

Citation tools
Junquera Alonso E, Seoane Blanco L, Cano Calderero F. Bortezomib-induced acute pancreatitis, an uncommon adverse event. 7120/2020


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1153 visits.
This article has been downloaded 229 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 10/04/2020

Accepted: 15/04/2020

Online First: 19/11/2020

Published: 11/01/2021

Article Online First time: 223 days

Article editing time: 276 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2024 y Creative Commons. The Spanish Journal of Gastroenterology