Year 2024 / Volume 116 / Number 9
Digestive Diseases Image
Spontaneous regression of a rectal cancer

498-499

DOI: 10.17235/reed.2023.9486/2023

Raquel Ortigão, Madalena Souto-Moura, Manuel Jacome, Diogo Libânio,

Abstract
A 42-year-old woman underwent a total colonoscopy due to haematochezia and weight loss. A rectal lateral spreading lesion with 2 5mm in diameter was identified and biopsies revealed villous adenoma with high-grade dysplasia. After referral to our centre, sigmoidoscopy confirmed the presence of a 25 mm lesion (NICE 3) with non-lifting sign and EUS showed a hypoechoic lesion with at least submucosal invasion and suspicious images of muscularis propria invasion - uT1/2N0. New biopsies shown the presence of adenocarcinoma. The patient was submitted to surgical anterior resection of the rectum. Intraoperative extemporaneous examination of the specimen did not identify the lesion and an intraoperative colonoscopy was performed not showing any lesion in the rectal stump. Pathological examination, after total inclusion of the specimen, showed a 7mm scar with fibrosis of the submucosa, chronic inflammatory infiltrate, vascular ectasia and congestion and mucosal erosion, without identification of residual neoplasia.To date (20 months of follow-up) there is no evidence of disease persistence or recurrence with a sigmoidoscopy performed 3 months after surgery.
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09/09/2024 18:40:27
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References
1. Nishiura B, Kumamoto K, Akamoto S, et al. Spontaneous regression of advanced transverse colon cancer with remaining lymph node metastasis. Surg Case Rep. 2020/05/11; 6(1):100. DOI: 10.1186/s40792-020-00858-1.
2. Karakuchi N, Shimomura M, Toyota K, et al. Spontaneous regression of transverse colon cancer with high-frequency microsatellite instability: a case report and literature review. World J Surg Oncol. 2019/01/15; 17(1):19. DOI: 10.1186/s12957-018-1552-x.
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Ortigão R, Souto-Moura M, Jacome M, Libânio D. Spontaneous regression of a rectal cancer. 9486/2023


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Publication history

Received: 24/01/2023

Accepted: 07/02/2023

Online First: 13/02/2023

Published: 09/09/2024

Article revision time: 7 days

Article Online First time: 20 days

Article editing time: 594 days


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