Year 2021 / Volume 113 / Number 6
Original
Role of endoscopic ultrasound-guided fine-needle aspiration in the diagnosis and classification of lymphomas

404-410

DOI: 10.17235/reed.2020.7191/2020

Javier Tejedor-Tejada, Carlos Chavarría, Beatriz Burgueño-Gómez, Ignacio Fanjul, Francisco Javier García-Alonso, María Ángeles Torres, Beatriz Madrigal, Manuel Pérez-Miranda, Carlos De la Serna-Higuera,

Abstract
Background: endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a safe and effective technique in the diagnosis of mediastinal and abdominal masses. However, the usefulness of EUS-FNA in the diagnosis and classification of lymphomas is controversial. The aim of this study was to determine the yield of EUS-FNA in the diagnosis and classification of lymphomas. Methods: a retrospective case series was performed in a tertiary referral center. All consecutive patients referred for EUS-FNA with a suspected diagnosis of lymphoma from March 2013 to June 2019 were included. Results: thirty-five patients (54.3 % women, median age 72 years) were included. The most frequent location of the node was the abdomen (67.9 %). Nodes were punctured using a 22-gauge (85.7 %) and 19-gauge needle (14.3 %) with a slow-pull technique. The number of passes performed were three or more in 82.9 % of patients. The samples were processed by the cellblock method. Adequate samples for immunohistochemical and molecular biological study were obtained in 33 (94.3 %) patients. EUS-FNA correctly diagnosed lymphoma in 30 out of 35 patients (85.7 %), and subclassification was determined in 23 patients (65.7 %). The most frequent diagnosis was non-Hodgkin lymphoma (85.7 %). There was one moderate adverse event (bleeding), which was resolved during the procedure. Conclusions: EUS-FNA may be a valuable technique in the evaluation of suspected lymphomas with an adequate diagnostic yield and a very low rate of adverse events.
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Tejedor-Tejada J, Chavarría C, Burgueño-Gómez B, Fanjul I, García-Alonso F, Torres M, et all. Role of endoscopic ultrasound-guided fine-needle aspiration in the diagnosis and classification of lymphomas. 7191/2020


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Publication history

Received: 26/04/2020

Accepted: 21/06/2020

Online First: 23/11/2020

Published: 04/06/2021

Article revision time: 52 days

Article Online First time: 211 days

Article editing time: 404 days


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