Year 2018 / Volume 110 / Number 3
Letter to the Editor
Autoimmune hepatitis as a complication of common variable immunodeficiency

212-213

DOI: 10.17235/reed.2018.5280/2017

Patrícia de Oliveira Queirós, José Manuel Sousa Martín,

Abstract
In common variable immunodeficiency (CVID) there is a deregulation of the immune system, which frequently leads to an increased risk of infections, but also to autoimmunity phenomena. Autoimmune hepatitis may develop at any time of CVID’s evolution, but it is difficult to diagnose due to the frequent absence of autoantibodies and low levels of IgG. Early diagnosis is important because targeted treatment may allow disease improvement. We present a case of autoimmune hepatitis in a patient with CVID.
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References
Saldaña-Dueñas C, Rubio-Iturria S. Immmunodeficiencies and autoimmune diseases: Common variable immunodeficiency and Crohn-like. Rev Esp Enferm Dig 2016;108(8): 220–3.
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Bjøro K, Haaland T, Skaug K, et al. The spectrum of hepatobiliary disease in primary hypogammaglobulinaemia. J Intern Med 1999;245(5):517–24.
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Queirós P, Sousa Martín J. Autoimmune hepatitis as a complication of common variable immunodeficiency. 5280/2017


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Publication history

Received: 29/09/2017

Accepted: 30/10/2017

Online First: 25/01/2018

Published: 28/02/2018

Article Online First time: 118 days

Article editing time: 152 days


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