Year 2022 / Volume 114 / Number 5
Letter
Curcumin and curcumoids: hepatoprotection or hepatotoxicity?

304-305

DOI: 10.17235/reed.2022.8588/2022

Miguel Fernández Bermejo, Alberto Masa Caballero, Ángela Lozano Lozano,

Abstract
Curcumin (Curcuma longa) and curcumin analogues are plant-based drugs used because of their possible antioxidant and anti-inflammatory. Clinical data on the efficacy of curcumin as a hepatoprotectant are limited, with growing concern for formulations that may potentially increase curcumin hepatotoxicity.
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26/11/2022 2:28:56
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10/05/2022 7:11:42
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References
1. Pulido-Moran M, Moreno-Fernandez J, Ramirez-Tortosa C, et al. Curcumin and Health. Molecules. 2016 Feb;21(3):264.
2. Hewlings S, Kalman D. Curcumin: a review of its effects on human health. Foods. 2017;6(10):92
3. 3.- Sohn SI, Priya A, Balasubramaniam B, et al. Pandian biomedical applications and bioavailability of curcumin - An updated overview. S. Pharmaceutics. 2021 Dec 7;13(12):2102
4. Lombardi N, Crescioli G, Maggini V, et al. Acute liver injury following turmeric use in Tuscany: An analysis of the Italian Phytovigilance database and systematic review of case reports. Br J Clin Pharmacol. 2021;87(3):741–53
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Fernández Bermejo M, Masa Caballero A, Lozano Lozano Á. Curcumin and curcumoids: hepatoprotection or hepatotoxicity?. 8588/2022


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Publication history

Received: 10/01/2022

Accepted: 11/01/2022

Online First: 18/01/2022

Published: 06/05/2022

Article Online First time: 8 days

Article editing time: 116 days


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