Year 2022 / Volume 114 / Number 8
Letter
Impact of the SARS-CoV-2 pandemic on pancreatic cancer: diagnosis and short-term survival

509-510

DOI: 10.17235/reed.2022.8772/2022

Javier Tejedor-Tejada, César Gómez-Díez, Samuel Robles Gaitero, Ana Villar Caamaño, Benito Hermida Pérez, Jose Manuel Olmos, Aránzazu Álvarez Álvarez, Rafael Tojo González,

Abstract
Introduction: The COVID-19 pandemic has delayed medical consultation, possibly leading to the diagnosis of gastrointestinal cancer. The aim of the study was to analyze the impact of SARS-Cov-2 pandemic on new diagnosis and short-term survival of patients with pancreatic cancer (PC). Methods: All consecutive patients who had a suspected diagnosis of pancreatic lesion before (from March to September 2019) and during COVID 19 pandemic (from March to September 2020). Demographics, clinical and treatment were collected and compared. Short-term survival was assessed. Results: A total of 25 patients (n=13 men) with diagnosis of adenocarcinoma of the pancreas and a median age of 70 years (IQR 62-74) were included. An increase was observed in the number of patients with newly diagnosed PC (n= 12 [19.1%] versus n=13 [20.9%]; P= 0.603). The subgroup analysis revealed a tendency toward a longer diagnosis (11 versus 12 days; P= 0.219) and treatment (28 versus 44; P= 0.375) delay for patients with PC during COVID-19 pandemic. A significant increase was observed for number of cases of advanced stage III and IV (n=4 [30.8%] versus n=7 [53.8%]; P= 0.006). Palliative treatment was the most frequent approach during COVID-19 period. During 1-year follow-up, 6 (50%) and 7 (61.5%) deaths were observed among patients diagnosed before and after COVID-19 (P= 0.449), respectively. Conclusions: The COVID-19 pandemic has led to delays in diagnosis and treatment in PC, which translates into an advanced staging and a worse prognosis. These data should stimulate health care provider to facilitate procedures for detection pancreatic cancer.
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References
WHO. (2020) WHO director general’s opening remarks at the media briefing on COVID-19 11th March 2020. Available from: https://www.who. int/dg/speeches/detail/who-director-general-s-opening-remarks-at-themedia- briefing-on-covid-19–-11-march-2020. [Accessed 13 January 2022].
Kuzuu K, Misawa N, Ashikari K et al. Gastrointestinal Cancer Stage at Diagnosis Before and During the COVID-19 Pandemic in Japan. JAMA Netw Open. 2021;4(9):e2126334. Published 2021 Sep 1. doi:10.1001/jamanetworkopen.2021.26334
McKay SC, Pathak S, Wilkin RJW et al. Impact of SARS-CoV-2 pandemic on pancreatic cancer services and treatment pathways: United Kingdom experience. HPB (Oxford). 2021 Nov;23(11):1656-1665. doi: 10.1016/j.hpb.2021.03.003. Epub 2021 Mar 19. PMID: 34544628; PMCID: PMC7973054.
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Citation tools
Tejedor-Tejada J, Gómez-Díez C, Robles Gaitero S, Villar Caamaño A, Hermida Pérez B, Olmos J, et all. Impact of the SARS-CoV-2 pandemic on pancreatic cancer: diagnosis and short-term survival. 8772/2022


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Publication history

Received: 06/03/2022

Accepted: 11/03/2022

Online First: 17/03/2022

Published: 27/07/2022

Article Online First time: 11 days

Article editing time: 143 days


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