Year 2019 / Volume 111 / Number 3
Original
Survival and quality of life after surgery for colorectal cancer in the elderly: a comparative study

193-198

DOI: 10.17235/reed.2018.5807/2018

Irene Jiménez, Miguel Ángel Pacha, David Pares, María Esteve, José Troya, Josep Roca, Jaume Canet, Joan-Francesc Julián, Jaume Fernández-Llamazares,

Abstract
Background: the aim of this study was to analyze the clinical results of the multidisciplinary management of elderly patients with colorectal cancer in a single center and to describe postoperative quality of life. Methods: a comparative study was designed to compare the results and quality of life of patients treated in our center for colon cancer, aged from 80 to 84 years (study group) compared to a control group (aged form 75 to 79 years of age). Morbidity, mortality, oncological results and quality of life were analyzed. Results: eighty-seven patients aged between 80 and 84 years of age (study group) were compared to a control group, which was formed by 91 patients aged from 75 to 79 years of age. There were no significant differences in technique and morbidity. Survival at 30 days, 90 days and at the end of follow-up (median 48 months) were similar in both groups. There were no differences in quality of life except for one item with regard to physical function (p = 0.0138). Conclusion: similar clinical results and quality of life were achieved after treating elderly patients with colon cancer with a multidisciplinary management approach.
Share Button
New comment
Comments
No comments for this article
References
1. Cappell MS. Reducing the Incidence and Mortality of Colon Cancer: Mass Screening and Colonoscopic Polypectomy. Gastroenterol Clin North Am [Internet]. 2008 Mar [cited 2016 Dec 21];37(1):129–60. Available from: http://linkinghub.elsevier.com/retrieve/pii/S0889855307001276
2. Thomsen MK, Njor SH, Rasmussen M, Linnemann D, Andersen B, Baatrup G, et al. Validity of data in the Danish Colorectal Cancer Screening Database. Clin Epidemiol [Internet]. 2017 Feb [cited 2017 Mar 5];Volume 9:105–11. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28255255
3. Chang GJ, Kaiser AM, Mills S, Rafferty JF, Buie WD, Standards Practice Task Force of the American Society of Colon and Rectal Surgeons. Practice Parameters for the Management of Colon Cancer. Dis Colon Rectum [Internet]. 2012 Aug [cited 2017 Mar 23];55(8):831–43. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22810468
4. Steele SR, Chang GJ, Hendren S, Weiser M, Irani J, Buie WD, et al. Practice Guideline for the Surveillance of Patients After Curative Treatment of Colon and Rectal Cancer. Dis Colon Rectum [Internet]. 2015 Aug [cited 2017 Mar 23];58(8):713–25. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26163950
5. Mehta HB, Vargas GM, Adhikari D, Dimou F, Riall TS. Comparative effectiveness of chemotherapy versus resection of the primary tumor as the initial treatment in older patients with stage IV colorectal cancer. Color Dis [Internet]. 2017 Mar 17 [cited 2017 Mar 21]; Available from: http://www.ncbi.nlm.nih.gov/pubmed/28304120
6. Thuraisingam R, Jandova J, Pandit V, Michailidou M, Nfonsam VN. Assessing the national trends in colon cancer among Native Americans: A 12 year SEER database study. Am J Surg [Internet]. 2017 Aug [cited 2017 Aug 7];214(2):228–31. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28010880
7. Audisio RA. Tailoring surgery to elderly patients with cancer. Br J Surg [Internet]. 2016 Jan [cited 2017 Mar 23];103(2):e10–1. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26679284
8. Goldvaser H, Katz Shroitman N, Ben-Aharon I, Purim O, Kundel Y, Shepshelovich D, et al. Octogenarian patients with colorectal cancer: Characterizing an emerging clinical entity. World J Gastroenterol [Internet]. 2017 Feb 28 [cited 2017 Mar 21];23(8):1387. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28293085
9. Bongers BC, Berkel AE, Klaase JM, van Meeteren NL. An evaluation of the validity of the pre-operative oxygen uptake efficiency slope as an indicator of cardiorespiratory fitness in elderly patients scheduled for major colorectal surgery. Anaesthesia [Internet]. 2017 Jul 25 [cited 2017 Aug 7]; Available from: http://www.ncbi.nlm.nih.gov/pubmed/28741667
10. Ghaferi AA, Dimick JB. Importance of teamwork, communication and culture on failure-to-rescue in the elderly. Br J Surg [Internet]. 2016 Jan [cited 2017 Mar 23];103(2):e47–51. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26616276
11. Thiels CA, Bergquist JR, Meyers AJ, Johnson CL, Behm KT, Hayman A V, et al. Outcomes with multimodal therapy for elderly patients with rectal cancer. Br J Surg [Internet]. 2016 Jan [cited 2017 Mar 23];103(2):e106-14. Available from: http://doi.wiley.com/10.1002/bjs.10057
12. Nagtegaal ID. Never too old to fight cancer? What do we know about colorectal cancer in the elderly? Color Dis [Internet]. 2017 Mar [cited 2017 Mar 21];19(3):223–223. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28251787
13. Yamamoto S, Watanabe M, Hasegawa H, Baba H, Kitajima M. Short-term surgical outcomes of laparoscopic colonic surgery in octogenarians: a matched case-control study. Surg Laparosc Endosc Percutan Tech [Internet]. 2003 Apr [cited 2017 Mar 23];13(2):95–100. Available from: http://www.ncbi.nlm.nih.gov/pubmed/12709614
14. Spanjersberg WR, van Sambeeck JDP, Bremers A, Rosman C, van Laarhoven CJHM. Systematic review and meta-analysis for laparoscopic versus open colon surgery with or without an ERAS programme. Surg Endosc [Internet]. 2015 Dec 24 [cited 2017 Aug 7];29(12):3443–53. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25801106
15. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis [Internet]. 1987 [cited 2017 Mar 23];40(5):373–83. Available from: http://www.ncbi.nlm.nih.gov/pubmed/3558716
16. Terret C, Albrand G, Moncenix G, Droz JP. Karnofsky Performance Scale (KPS) or Physical Performance Test (PPT)? That is the question. Crit Rev Oncol Hematol [Internet]. 2011 Feb [cited 2017 Aug 7];77(2):142–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20185330
17. Wade DT, Collin C. The Barthel ADL Index: a standard measure of physical disability? Int Disabil Stud [Internet]. 1988 [cited 2017 Aug 7];10(2):64–7. Available from: http://www.ncbi.nlm.nih.gov/pubmed/3042746
18. Ware J, Kosinski M, Keller SD. A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care [Internet]. 1996 Mar [cited 2017 Mar 23];34(3):220–33. Available from: http://www.ncbi.nlm.nih.gov/pubmed/8628042
19. Gandek B, Ware JE, Aaronson NK, Apolone G, Bjorner JB, Brazier JE, et al. Cross-validation of item selection and scoring for the SF-12 Health Survey in nine countries: results from the IQOLA Project. International Quality of Life Assessment. J Clin Epidemiol [Internet]. 1998 Nov [cited 2017 Mar 23];51(11):1171–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/9817135
20. De Angelis R, Sant M, Coleman MP, Francisci S, Baili P, Pierannunzio D, et al. Cancer survival in Europe 1999–2007 by country and age: results of EUROCARE-5—a population-based study. Lancet Oncol [Internet]. 2014 Jan [cited 2017 Mar 23];15(1):23–34. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24314615
21. Kazama K, Aoyama T, Hayashi T, Yamada T, Numata M, Amano S, et al. Evaluation of short-term outcomes of laparoscopic-assisted surgery for colorectal cancer in elderly patients aged over 75 years old: a multi-institutional study (YSURG1401). BMC Surg [Internet]. 2017 Dec 21 [cited 2017 Mar 23];17(1):29. Available from: http://www.ncbi.nlm.nih.gov/pubmed/28327119
22. Guida F, Clemente M, Valvano L, Napolitano C. Laparoscopic or open hemicolectomy for elderly patients with right colon cancer? A retrospective analysis. G Chir [Internet]. [cited 2017 Mar 23];36(5):205–8. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26712256
23. Verweij NM, Souwer ETD, Schiphorst AHW, Maas HA, Portielje JEA, Pronk A, et al. The effect of a geriatric evaluation on treatment decisions for older patients with colorectal cancer. Int J Colorectal Dis [Internet]. 2017 Sep 20 [cited 2017 Oct 20];32(11):1625–9. Available from: http://link.springer.com/10.1007/s00384-017-2883-8
24. Moth EB, Vardy J, Blinman P. Decision-making in geriatric oncology: systemic treatment considerations for older adults with colon cancer. Expert Rev Gastroenterol Hepatol [Internet]. 2016 Dec 21 [cited 2017 Nov 19];10(12):1321–40. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27718755
25. Bentrem DJ, Cohen ME, Hynes DM, Ko CY, Bilimoria KY. Identification of specific quality improvement opportunities for the elderly undergoing gastrointestinal surgery. Arch Surg [Internet]. 2009 Nov 16 [cited 2017 Oct 17];144(11):1013–20. Available from: http://archsurg.jamanetwork.com/article.aspx?doi=10.1001/archsurg.2009.114
26. Berian JR, Rosenthal RA, Baker TL, Coleman J, Finlayson E, Katlic MR, et al. Hospital Standards to Promote Optimal Surgical Care of the Older Adult: A Report From the Coalition for Quality in Geriatric Surgery. Ann Surg [Internet]. 2017 Mar 8 [cited 2017 Nov 19];1. Available from: http://insights.ovid.com/crossref?an=00000658-900000000-96195
Related articles

Letter

Retroperitoneal enterogenous cyst combined with teratoma

DOI: 10.17235/reed.2023.9799/2023

Letter

Surgical indication of type I gastric neuroendocrine tumors

DOI: 10.17235/reed.2023.9681/2023

Letter

Intestinal obstruction due to pneumatosis intestinalis

DOI: 10.17235/reed.2023.9608/2023

Letter

Duodenal stenosis surgical treatment in Crohn’s disease

DOI: 10.17235/reed.2023.9521/2023

Digestive Diseases Image

Spontaneous regression of a rectal cancer

DOI: 10.17235/reed.2023.9486/2023

Letter

Vaginal lesion as first manifestation of colorectal disease

DOI: 10.17235/reed.2022.9270/2022

Digestive Diseases Image

An unusual cause of a protuberant lesion of the gastric antrum

DOI: 10.17235/reed.2022.8771/2022

Digestive Diseases Image

Gastric gastrointestinal stromal tumor abscess

DOI: 10.17235/reed.2022.8580/2022

Review

A review of the diagnosis and management of liver hydatid cyst

DOI: 10.17235/reed.2021.7896/2021

Letter

Radical surgery for liver hydatidosis

DOI: 10.17235/reed.2021.7743/2020

Digestive Diseases Image

Duodenal diverticulum causing obstructive jaundice – Lemmel’s syndrome

DOI: 10.17235/reed.2020.7516/2020

Review

Inflammatory bowel disease and solid organ transplantation

DOI: 10.17235/reed.2020.7361/2020

Review

New non-invasive biomarkers for colorectal cancer screening

DOI: 10.17235/reed.2020.7233/2020

Letter

Medullary colorectal carcinoma. Do we really know it?

DOI: 10.17235/reed.2020.6728/2019

Letter

Bezoar in incarcerated and complicated hiatal hernia

DOI: 10.17235/reed.2019.6159/2019

Editorial

Safe surgery for cystic tumors of the pancreas

DOI: 10.17235/reed.2019.6042/2018

Letter

The rectosigmoid junction: are limits important?

DOI: 10.17235/reed.2019.5983/2018

Editorial

Colorectal cancer screening and survival

DOI: 10.17235/reed.2018.5870/2018

Letter to the Editor

Consequences of a Dieulafoy’s lesion in gastric surgery

DOI: 10.17235/reed.2018.5442/2017

Letter to the Editor

Abdominal compartment syndrome secondary to acute necrotizing pancreatitis

DOI: 10.17235/reed.2017.4810/2016

Original

Usefulness of an intra-gastric balloon before bariatric surgery

DOI: 10.17235/reed.2017.4624/2016

Original

Coping with celiac disease: how heavy is the burden for caregivers?

DOI: 10.17235/reed.2017.4518/2016

Letter to the Editor

Liver metastasis from colorectal cancer 12 years after liver transplantation

DOI: 10.17235/reed.2017.4507/2016

Letter to the Editor

Transanal submucosal endoscopic resection (TASER) by TEO system®

DOI: 10.17235/reed.2016.4154/2015

Review

Serrated lesions and serrated polyposis syndrome

DOI: 10.17235/reed.2017.4065/2015

Letter to the Editor

Endobronchial metastases of colorectal cancer

DOI: 10.17235/reed.2016.4080/2015

Letter to the Editor

Minimally invasive treatment of rectovesical fistula: A case report

DOI: 10.17235/reed.2016.4017/2015

Case Report

Primary squamous cell carcinoma of the rectum: an atypical histology

DOI: 10.17235/reed.2016.3975/2015

Citation tools
Jiménez I, Pacha M, Pares D, Esteve M, Troya J, Roca J, et all. Survival and quality of life after surgery for colorectal cancer in the elderly: a comparative study. 5807/2018


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1166 visits.
This article has been downloaded 236 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 01/07/2018

Accepted: 30/09/2018

Online First: 14/12/2018

Published: 04/03/2019

Article revision time: 83 days

Article Online First time: 166 days

Article editing time: 246 days


Share
This article has been rated by 1 readers.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology