Year 2023 / Volume 115 / Number 1
Letter
Importance of immunohistochemistry in the differential diagnosis of gastric mesenchymal tumors

41-42

DOI: 10.17235/reed.2022.8923/2022

José Ruiz Pardo, Íñigo Gorostiaga Altuna, Pedro Antonio Sánchez Fuentes, Cristina María Gras Gómez, Elisabet Vidaña Márquez, Ricardo Belda Lozano, Manuel Ferrer-Márquez, Ángel Reina Duarte,

Abstract
Although morphology is the key to histological diagnosis, gastric mesenchymal tumors can share very similar growth and cellularity patterns, sometimes being indistinguishable. Therefore, immunohistochemical techniques are going to be crucial in the definitive diagnosis. The objective of this work is to perform an immunohistochemical differential diagnosis of gastric mesenchymal tumors.
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References
1. Cañas García I, Lendínez Romero I, Malo Prián RM, et al. Importance of immunohistochemistry in the differential diagnosis of gastric stromal tumors: gist vs. schwannoma. Rev Esp Enferm Dig. 2022;114:305-6. DOI: 10.17235/reed.2022.8583/2022
2. WHO Classification of Tumours Editorial Board. WHO Classification of Tumours: Digestive System Tumours. 5th ed. Lyon (France): International Agency for Research on Cancer; 2019.
3. Hirota S. Differential diagnosis of gastrointestinal stromal tumor by histopathology and immunohistochemistry. Transl Gastroenterol Hepatol. 2018;3:27. DOI: 10.21037/tgh.2018.04.01
4. Kang HC, Menias CO, Gaballah AH, et al. Beyond the GIST: mesenchymal tumors of the stomach. Radiographics. 2013;33:1673-90. DOI: 10.1148/rg.336135507
5. Dow N, Giblen G, Sobin LH, et al. Gastrointestinal stromal tumors: differential diagnosis. Semin Diagn Pathol. 2006;23:111-9. DOI: 10.1053/j.semdp.2006.09.002
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Ruiz Pardo J, Gorostiaga Altuna Í, Sánchez Fuentes P, Gras Gómez C, Vidaña Márquez E, Belda Lozano R, et all. Importance of immunohistochemistry in the differential diagnosis of gastric mesenchymal tumors. 8923/2022


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Publication history

Received: 11/05/2022

Accepted: 13/05/2022

Online First: 03/06/2022

Published: 12/01/2023

Article Online First time: 23 days

Article editing time: 246 days


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