Year 2022 / Volume 114 / Number 8
Letter
Sigmoid colon Schwannoma simulating colon cancer

499-500

DOI: 10.17235/reed.2022.8684/2022

María de Armas Conde, Ana Soto Sánchez, Moisés Hernández Barroso, Nélida Díaz Jiménez, Luis Eduardo Pérez Sánchez, Guillermo Hernández Hernández, Manuel Ángel Barrera Gómez,

Abstract
Schwannomas tumours are uncommonly developed in the gastrointestinal tract (2-6%), located in 12% of cases in small and large intestines. An 87-year-old woman was studied due to epigastric pain and dyspepsia. CT scan and colonoscopy showed a neoplastic process in the sigmoid colon. It was performed an oncologic laparoscopic sigmoidectomy. Histological study described a schwannoma and a positive immunohistochemistry to S-100. The diagnostic challenge is that this is a submucosa lesion, therefore, endoscopy biopsy is realized only in the mucosa. This becomes the differential diagnostic very difficult in order to differentiate from another mesenchymal tumor (GIST or leiomyoma). The immunohistochemistry helps in the diagnostic if it is positive to S- 100 and negative to C-KIT, CD-34, actine and desmine (findings of GIST tumors and leiomyoma). In conclusion, schwannoma diagnostic is tough. Those are asymptomatic tumors with nonspecific radiological findings. Diagnostic confirmation is a S-100 positive immunohistochemistry in the histological study.
Share Button
New comment
Comments
No comments for this article
References
1. Bohlok A, El Khoury M, Bormans A, et al. Schwannoma of the colon and rectum: a systematic literature review. World J Surg Oncol. 2018 Jul 3;16(1):125.
2. Guevara-Martínez J, Toribio-Vázquez C, Noire FP, et al. Transanal Minimally Invasive Surgery for Local Excision of a Rectal Schwannoma. Dis Colon Rectum. 2022 Jan 1;65(1):e1-e3.
3. Kojima Y, Yamaguchi T, Taguchi S, et al. Ascending Colon Schwannoma Surgically Treated after Accurate Preoperative Diagnosis. Case Rep Gastroenterol. 2020 Oct 15;14(3):483-490.
4. Pansari M, Lodin D, Gupta AK, et al. Rare Case of a Transverse Colon Schwannoma. Cureus. 2020 Apr 9;12(4):e7604.
Cañas García I, Lendínez Romero I, Malo Prián RM, Rodríguez Morillas D. Importance of immunohistochemistry in the differential diagnosis of gastric stromal tumors: GIST vs. schwannoma. Rev Esp Enferm Dig. 2022 Jan 19. doi: 10.17235/reed.2022.8583/2022.
Citation tools
de Armas Conde M, Soto Sánchez A, Hernández Barroso M, Díaz Jiménez N, Pérez Sánchez L, Hernández Hernández G, et all. Sigmoid colon Schwannoma simulating colon cancer. 8684/2022


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1420 visits.
This article has been downloaded 140 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 05/02/2022

Accepted: 20/02/2022

Online First: 14/03/2022

Published: 27/07/2022

Article revision time: 12 days

Article Online First time: 37 days

Article editing time: 172 days


Share
This article has been rated by 1 readers.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology