Year 2021 / Volume 113 / Number 8
Digestive Diseases Image
Dubin-Johnson syndrome as a laparoscopic finding

610-611

DOI: 10.17235/reed.2021.7866/2021

Alba Cebrián García, David Ruiz-Clavijo García, Alba Larrea Ramírez, Beñat Arín Palacios,

Abstract
We present the case of a 35-year-old female with a history of polycystic ovary syndrome, treated with oral contraceptives. She was under study due to nine months evolution of pain in the right iliac fossa, associated with hyporexia and mild hyperbilirubinemia with a predominance of the conjugated fraction (total Bi 3.7 mg/dl, conjugated Bi 2.9 mg/dl). An abdominal computed tomography (CT) was performed showing homogeneous hepatosplenomegaly and adenopathies in both iliac chains, the largest in the right external iliac chain of 1.6 x 3.6 cm.
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References
1. Memon N, Weinberger BI, Hegyi T et al. Inherited disorders of bilirubin clearance. Pediatr Res. 2016 Mar;79(3):378-86.
2. Keitel V, Nies A, Brom M et al. A common Dubin-Johnson syndrome mutation impairs protein maturation and transport activity of MRP2 (ABCC2). Am J Physiol (Gastrointest Liver Physiol) 2003; 284:165-174.
3. Dubin IN. Chronic idiopathic jaundice; a review of fifty cases. Am J Med. 1958 Feb;24(2):268-92.
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Cebrián García A, Ruiz-Clavijo García D, Larrea Ramírez A, Arín Palacios B. Dubin-Johnson syndrome as a laparoscopic finding. 7866/2021


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Publication history

Received: 04/02/2021

Accepted: 20/02/2021

Online First: 04/03/2021

Published: 28/07/2021

Article revision time: 16 days

Article Online First time: 28 days

Article editing time: 174 days


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