Year 2016 / Volume 108 / Number 12
Case Report
Primary squamous cell carcinoma of the rectum: an atypical histology

826-835

DOI: 10.17235/reed.2016.3975/2015

Araceli Ballestero Pérez, Pedro Abadía Barnó, Francisca García-Moreno Nisa, Javier Die Trill, Julio Galindo Álvarez,

Abstract
Squamous cell carcinoma of the rectum is one of the differential diagnoses of rectal tumors. It represents a low incidence in the population. The etiopathogenesis and the biology of these tumors are unclear, for this reason the gold standard treatment is difficult to establish. We present a 47-years-old woman who had a squamous cell carcinoma in medium rectum. She was treated with radiation therapy and chemotherapy and the treatment was followed by surgical excision.
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References
1. Dyson T, Draganov PV. Squamous cell cáncer of the rectum. World J Gastroenterol 2009;15:4380-6.
2. Schmidtmann M. Zur Kenntnis seltener Krebsformen. Virchows Arch 1919;226:100-18.
3. Raiford TS. Epitheliomata of the lower rectum and anus. Surg Gynecol Obstet 1933;57:21-35.
4. Wiener MF, Polayes SH, Yidi R. Squamous carcinoma with schistosomiasis of the colon. Am J Gastroenterol 1962;37:48-54.
5. Yurdakul G, de Reijke TM, Blank LE, et al. Rectal squamous cell carcinoma 11 years after brachytherapy for carcinoma of the prostate. J Urol 2003;169:280.
6. Fu K, Tsujinaka Y, Hamahata Y, et al. Squamous metaplasia of the rectum associated with ulcerative colitis diagnosed using narrow-band imaging. Endoscopy 2008;40:E45-6.
7. Hicks JD, Cowling DC. Squamous-cell carcinoma of the ascending colon. J Pathol Bacteriol 1955;70:205-12.
8. Jaworski RC, Biankin SA, Baird PJ. Squamous cell carcinoma in situ arising in inflammatory cloacogenic polyps: report of two cases with PCR analysis for HPV DNA. Pathology 2001;33:312-4.
9. Audeau A, Han HW, Johnston MJ, et al. Does human papiloma virus have a role in squamous cell carcinoma of the colon and upper rectum? Eur J Surg Oncol 2002;28:657-60.
10. Kassir R, Baccot S, Bouarioua N, et al. Squamous cell carcinoma of middle rectum: Literature review. Int J Surg Case Rep 2014;5:86-90
11. Williams GT, Blackshaw AJ, Morson BC. Squamous carcinoma of the colorectum and its genesis. J Pathol 1979;129:139-47.
12. Musio D, De Felice F, Manfrida S, et al. Squamous cell carcinoma of the rectum: The treatment paradigm. Eur J Surg Oncol 2015;41:1054-8
13. Wang JF, Wang ZX, Xu XX, et al. Primary rectal squamous cell carcinoma treated with surgery and radiotherapy. World J Gastroenterol 2014;20:4106-9.
14. Péron J, Bylicki O, Laude C, et al. Nonoperative Management of Squamous-Cell Carcinoma of the Rectum. Dis Colon Rectum 2015;50:60-4.
15. Nahas CS, Shia J, Joseph R, et al. Squamous-cell carcinoma of the rectum: a rare but curable tumor. Dis Colon Rectum 2007;50:1393-400.
16. LeBlanc LJ, Buie LA, Dockerty MB. Squamous-cell epithelioma of the rectum. Ann Surg. 1950;131:392–9.
17. Hohm WH, Jackman RJ. Squamous Cell Carcinoma of the Rectum Complicating Ulcerative Colitis: Report of Two Cases. Mayo Clin Proc 1964; 39: 249-51.
18. Vezeridis MP, Herrera LO, Lopez GE, et al. Squamous-cell carcinoma of the colon and rectum. Dis Colon Rectum 1983;26:188–91
19. Gelas T, Peyrat P, Francois Y, et al. Primary squamous-cell carcinoma of the rectum. Report of six cases and review of the literature. Dis Colon Rectum. 2002; 45:1535-40.
20. Clark J, Cleator S, Goldin R, et al. Treatment of primary rectal squamous cell carcinoma by primary chemoradiotherapy: should surgery still be considered a standard of care? Eur J Cancer. 2008;44:2340–3.
21. Rasheed S, Yap T, Zia A, et al. Chemo-radiotherapy: an alternative to surgery for squamous cell carcinoma of the rectum–report of six patients and literature review. Colorectal Dis. 2009; 11:191-7.
22. Tronconi M, Carnaghi C, Bignardi M, et al. Rectal squamous cell carcinoma treated with chemoradiotherapy: Report of six cases. Int J Colorectal Dis 2010;25:1435–9.
23. Yeh J, Hastings J, Rao A, et al. Squamous cell carcinoma of the rectum: a single institution experience. Tech Coloproctol. 2012;16:349–54.
24. Jeong BG, Kim DY, Kim SY. Concurrent chemoradiotherapy for squamous cell carcinoma of the rectum. Hepatogastroenterology. 2013;60:512-6.
25. Sturgeon JD, Crane CH, Krishnan S, et al. Definitive Chemoradiation for Squamous Cell Carcinoma of the Rectum. Am J Clin Oncol. 2014 Sep 12. [Epub ahead of print].
26. Ozuner G, Aytac E, Gorgun E. Colorectal squamous cell carcinoma: a rare tumor with poor prognosis. Colorectal Dis. 2015;30:127-30.
27. Funahashi K, Nemoto T, Koike J, et al. Chemoradiation therapy with S-1 for primary squamous cell carcinoma of the rectum: report of three cases. J Surg Case Rep. 2015, 1:14.
28. Dixon CF, Dockerty MB, Powelson MH. Squamous cell carcinoma of the midrectum: report of case. Proc Staff Meet Mayo Clin. 1954;29:420-3.
29. Cabrera A, Pickren JW. Squamous metaplasia and squamous-cell carcinoma of the rectosigmoid. Dis Colon Rectum 1967; 10: 288-97.
30. Higton DI. Squamous cell carcinoma of rectum. Proc R Soc Med. 1970;63:754.
31. Martínez-González , Takahashi T, Leon-Rodriguez E, et al. Case report of primary squamous carcinoma of the rectum. Rev Invest Clin 1996, 48:453-6.
32. Sotlar K, Koveker G, Aepinus C, et al. Human papillomavirus type 16-associated primary squamous cell carcinoma of the rectum. Gastroenterology 2001;120:988-94.
33. Anagnostopoulos G, Sakorafas GH, Kostopoulos P, et al. Squamous cell carcinoma of the rectum: a case report and review of the literature. Eur J Cancer Care 2005;14:70–4.
34. Theodosopoulos TK, Marinis AD, Dafnios NA, et al. Aggressive treatment of metastatic squamous cell carcinoma of the rectum to the liver: a case report and a brief review of the literature. Worl J Surg Oncol 2006;4:49–52.
35. Leung KK, Heitzman J, Madan A. Squamous cell carcinoma of the rectum 21 years after radiotherapy for cervical carcinoma. Saudi J Gastroenterol. 2009;15:196-8.
36. Sameer AS, Syeed N, Chowdri NA, et al. Squamous cell carcinoma of rectum presenting in a man: a case report. J Med Case Rep. 2010;4:392.
37. Iannacone E, Dionisi F, Musio D, et al. Chemoradiation as definitive treatment for primary squamous cell cancer of the rectum. World J Radiol. 2010;2:329-33.
38. Al Hallak MN, Hage-Nassar G, Mouchli A. Primary Submucosal Squamous Cell Carcinoma of the Rectum Diagnosed by Endoscopic Ultrasound: Case Report and Literature Review. Case Rep Gastroenterol. 2010;4:243-9.
39. Custodio A, Ortega L, Sanz G, et al. Human papillomavirus type 16- associated primary squamous cell carcinoma of the rectum following cervical intraepithelial neoplasia. Med Clin (Barc). 2011;136:223-4.
40. Hogan NM, Leonard G, Sheehan M, et al. Early recurrence and progression of a rare rectal squamous cell carcinoma after initial response to primary chemoradiotherapy. Tumori. 2013;99:e88-90.
41. Ferreira AO, Loureiro AL, Marques V, et al. Primary squamous cell carcinoma of the most distal rectum: a dilemma in origin and management. BMJ Case Rep. Apr 2;2014.
42. Scaringi S, Bisogni D, Messerini L, et al. Squamous cell carcinoma of the middle rectum: Report of a case and literature overview. Int J Surg Case Rep. 2015; 7C:127-9.
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Ballestero Pérez A, Abadía Barnó P, García-Moreno Nisa F, Die Trill J, Galindo Álvarez J. Primary squamous cell carcinoma of the rectum: an atypical histology. 3975/2015


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Publication history

Received: 14/08/2015

Accepted: 09/11/2015

Online First: 25/02/2016

Published: 30/11/2016

Article revision time: 77 days

Article Online First time: 195 days

Article editing time: 474 days


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