Year 2018 / Volume 110 / Number 6
Original
Outbreak of acute hepatitis A in the health area served by the Hospital Universitario Virgen de la Victoria (HUVV): a change in epidemiology

380-385

DOI: 10.17235/reed.2018.5207/2017

Alejandro José García Ferreira, Aida Ortega Alonso, Julia Cobos Rodríguez, Paula Bardón de Tena, Miguel Calderón Cid, Alberto Manuel García García, María Dolores García Escaño, Ramiro Alcántara Benitez, Encarnacíon Clavijo Frutos, Miren García-Cortés, Raúl Andrade,

Abstract
In 2016, an outbreak of hepatitis A was identified in the Malaga province among patients with specific epidemiological characteristics, which were predominantly males. This is a report of 51 subjects with acute hepatitis A and a mean age of 35.7 years, 90% were male and 55% of cases were men who had had sex with other men within the last two months. Half of them required hospitalization for significant coagulopathy at diagnosis and no cases progressed to fulminant failure or encephalopathy. Four patients had ascites at the time of diagnosis. This outbreak adds to those reported in the United Kingdom and the Netherlands with a similar number of cases and epidemiology. These studies highlight the importance of epidemiological surveillance, the need for vaccination in this particular at risk population and the need for informative campaigns in order to prevent this disease.
Share Button
New comment
Comments
No comments for this article
References
Høybye G, Skinhøj P, Hentzer B, Faber V, Mathiesen L. An epidemic of acute viral hepatitis in male homosexuals. Etiology and clinical characteristics. Scand J Infect Dis 1980; 12(4): 241-4.
2. Tortajada C, de Olalla PG, Diez E, et al. Hepatitis A among men who have sex with men in Barcelona, 1989-2010: insufficient control and need for new approaches. BMC Infect Dis 2012; 12: 11.
3. Tortajada C, de Olalla PG, Pinto RM, Bosch A, Caylà J. Outbreak of hepatitis A among men who have sex with men in Barcelona, Spain, September 2008-March 2009. Euro Surveill 2009; 14(15).
4. Llach-Berné M, Pañella H, Domínguez A, et al. [Descriptive study of hepatitis outbreaks occurring in Catalonia (1999-2003)]. Enferm Infecc Microbiol Clin 2006; 24(7): 431-6.
5. Beebeejaun K, Degala S, Balogun K, et al. Outbreak of hepatitis A associated with men who have sex with men (MSM), England, July 2016 to January 2017. Euro Surveill 2017; 22(5).
6. ECDC. European Centre for Disease Prevention and Control.  Hepatitis A virus in the EU/EEA. Stockholm; 2016. p. 1975-2014.
7. Nainan OV, Xia G, Vaughan G, Margolis HS. Diagnosis of hepatitis a virus infection: a molecular approach. Clin Microbiol Rev 2006; 19(1): 63-79.
8. Plotkin S, Orenstein W, Offit P. Hepatitis A vaccines. Vaccines. 6th ed; 2012: 183-205.
9. ECDC. European  Centre for Disease Prevention and Control.  Hepatitis A outbreaks in the EU/EEA mostly affecting men who have sex with men. Stockholm; 2017.
10. Freidl GS, Sonder GJ, Bovée LP, et al. Hepatitis A outbreak among men who have sex with men (MSM) predominantly linked with the EuroPride, the Netherlands, July 2016 to February 2017. Euro Surveill 2017; 22(8).
11. Gullón P, Varela C, Martínez EV, Gómez-Barroso D. Association between meteorological factors and hepatitis A in Spain 2010-2014. Environ Int 2017; 102: 230-5.
12. Wang Z, Chen Y, Xie S, Lv H. Changing Epidemiological Characteristics of Hepatitis A in Zhejiang Province, China: Increased Susceptibility in Adults. PLoS One 2016; 11(4): e0153804.
13. Chen CM, Chen SC, Yang HY, Yang ST, Wang CM. Hospitalization and mortality due to hepatitis A in Taiwan: a 15-year nationwide cohort study. J Viral Hepat 2016; 23(11): 940-5.
14. Chen GJ, Lin KY, Sun HY, et al. Incidence of acute hepatitis A among HIV-positive patients during an outbreak among MSM in Taiwan: Impact of HAV vaccination. Liver Int 2017.
15. Chen GJ, Lin KY, Hung CC, Chang SC. Hepatitis A Outbreak Among Men Who Have Sex With Men in a Country of Low Endemicity of Hepatitis A Infection. J Infect Dis 2017; 215(8): 1339-40.
16. Gozlan Y, Bar-Or I, Rakovsky A, et al. Ongoing hepatitis A among men who have sex with men (MSM) linked to outbreaks in Europe in Tel Aviv area, Israel, December 2016 - June 2017. Euro Surveill 2017; 22(29).
17. Werber D, Michaelis K, Hausner M, et al. Ongoing outbreaks of hepatitis A among men who have sex with men (MSM), Berlin, November 2016 to January 2017 - linked to other German cities and European countries. Euro Surveill 2017; 22(5).
Related articles

Editorial

Orthohepevirus C as causal agent of acute hepatitis in Spain

DOI: 10.17235/reed.2022.8993/2022

Letter

SARS-CoV-2 vaccine, a new autoimmune hepatitis trigger?

DOI: 10.17235/reed.2022.8820/2022

Letter

A case of COVID-19 with concomitant infection with hepatitis A

DOI: 10.17235/reed.2021.8372/2021

Letter

Autoimmune hepatitis triggered by COVID-19

DOI: 10.17235/reed.2021.8045/2021

Letter

Acute hepatitis due to olmesartan: an uncommon entity

DOI: 10.17235/reed.2020.7236/2020

Original

A new pattern in hepatitis A virus infection in an urban population

DOI: 10.17235/reed.2020.6526/2019

Letter

Acute seronegative hepatitis C: two case reports

DOI: 10.17235/reed.2019.5921/2018

Letter to the Editor

Autoimmune hepatitis as a complication of common variable immunodeficiency

DOI: 10.17235/reed.2018.5280/2017

Citation tools
García Ferreira A, Ortega Alonso A, Cobos Rodríguez J, Bardón de Tena P, Calderón Cid M, García García A, et all. Outbreak of acute hepatitis A in the health area served by the Hospital Universitario Virgen de la Victoria (HUVV): a change in epidemiology. 5207/2017


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1412 visits.
This article has been downloaded 241 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 01/08/2017

Accepted: 05/01/2018

Online First: 12/03/2018

Published: 31/05/2018

Article revision time: 134 days

Article Online First time: 223 days

Article editing time: 303 days


Share
This article has been rated by 1 readers.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology