Year 2020 / Volume 112 / Number 6
Original
Association of celiac disease in patients with multiple sclerosis in Tuscany

474-476

DOI: 10.17235/reed.2020.6123/2018

Barbara Piccini, Monica Ulivelli, Maria Pia Amato, Sabina Bartalini, Mario Falcini, Marta Giannini, Eliana Magnani, Luca Massacesi, Anna Maria Repice, Marina Vascotto, Salvatore Grosso,

Abstract
Background and study purpose: to describe the comorbidity of celiac disease among a large cohort of multiple sclerosis patients in Tuscany. Methods: the association of celiac disease among multiple sclerosis adult patients (n=2050) was retrospectively evaluated. Results: 13 patients were diagnosed with celiac disease, the female:male ratio was 3.3:1 and the median age at diagnosis was 34.2 years (SD 13). Seventy-seven per cent of subjects complained about gastrointestinal symptoms. IgA anti- transglutaminase was positive in 85 % of cases and there was 70 % of villous atrophy. Conclusions: the frequency of celiac disease among multiple sclerosis patients examined was lower than in the general population, 0.6 % vs 1 %)(p = 0.65).
Share Button
New comment
Comments

24/07/2024 13:07:54
Acunetix


References
1. Hadjivassiliou M, Grünewald RA, Lawden M, et al. Headache and CNS white matter abnormalities associated with gluten sensitivity. Neurology 2001;56:385-88.
2. Shatin R. Gluten and multiple sclerosis. Br Med J 1965;1:1433-4.
3. Polman CH, Reingold SC, Banwell B, et al. Diagnostic criteria for multiple sclerosis: 2010 revisions to the Mc Donald criteria. Ann Neurol 2011;69:292-302.
4. Revised criteria for diagnosis of coeliac disease. Report of working group of European Society of Pediatric Gastroenterology and Nutrition. Arch Dis Child 1990;65:909-11.
5. Husby S, Koletzko S, Korponay-Szabó IR, et al; ESPGHAN Working Group on Coeliac Disease Diagnosis; ESPGHAN Gastroenterology Committee; European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. J Pediatr Gastroenterol Nutr 2012;54:136-60.
6. Mustalahti K, Catassi C, Reunanen A, et al. The prevalence of celiac disease in Europe: results of a centralized, International mass screening project. Ann Med 2010;42:587-95.
7. Oberhuber G, Granditsch G, Vogelsang H. The histopatology of celiac disease: time for a standardized report scheme for pathologists. Eur J Gastroenterol Hepatol 1999;11:1185-94.
8. Cooke WT, Smith WT. Neurological disorders associated with adult coeliac disease. Brain 1966;89:683-722.
9. Hadjivassiliou M, Rao DG, Grìnewald RA, Aeschlimann DP, Sarrigiannis PG, Hoggard N, Aeschlimann P, Mooney PD, Sanders DS. Neurological Dysfunction in Coeliac Disease and Non-Coeliac Gluten Sensitivity. Am J Gastroenterol 2016;111:561-7.
10. Nicoletti A, Patti F, Lo Fermo S, et al. Frequency of celiac disease is not increased among multiple sclerosis patients. Mult Scler 2008;14:698-700.
11. Rodrigo L, Hernández-Lahoz C, Fuentes D, et al. Prevalence of celiac disease in multiple sclerosis. BMC Neurol 2011;11:31.
12. Ludvigsson JF, Olsson T, Ekbom A, et al. A population-based study of celiac disease, neurodegenerative and neuroinflammatory diseases. Aliment Pharmacol Ther 2007;25:1317-27.
Related articles

Letter

Liver disorders and celiac disease

DOI: 10.17235/reed.2023.9516/2023

Digestive Diseases Image

Calcified cavitating mesenteric lymph node syndrome: a rare complication of celiac disease

DOI: 10.17235/reed.2020.7494/2020

Letter

Balanced by iron. Hereditary hemochromatosis and celiac disease

DOI: 10.17235/reed.2020.7269/2020

Review

New celiac disease biomarkers

DOI: 10.17235/reed.2020.7217/2020

Editorial

Is celiac disease really associated with inflammatory bowel disease?

DOI: 10.17235/reed.2019.6779/2019

Original

Coping with celiac disease: how heavy is the burden for caregivers?

DOI: 10.17235/reed.2017.4518/2016

Letter to the Editor

Celiac disease and fibromyalgia: Is there an association?

DOI: 10.17235/reed.2015.3992/2015

Citation tools
Piccini B, Ulivelli M, Amato M, Bartalini S, Falcini M, Giannini M, et all. Association of celiac disease in patients with multiple sclerosis in Tuscany. 6123/2018


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 1339 visits.
This article has been downloaded 146 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 14/12/2018

Accepted: 18/09/2019

Online First: 07/05/2020

Published: 08/06/2020

Article revision time: 266 days

Article Online First time: 510 days

Article editing time: 542 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology