Year 2021 / Volume 113 / Number 10
Letter
Tofacitinib, a useful option for the treatment of pyoderma gangrenosum in an ulcerative colitis patient

733-734

DOI: 10.17235/reed.2021.7977/2021

Pablo Salmón Olavarría, Saioa Rubio Iturria, Óscar Nantes Castillejo,

Abstract
Pyoderma gangrenosum (PG) is a difficult-to-manage ulcero-necrotizing dermatosis associated with inflammatory bowel disease (IBD). In this article, we report a refractory PG in a patient with severe ulcerative colitis (UC) that responded to tofacitinib 10 mg/12 h.
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References
1. Plumptre I, Knabel D, Tomecki K. Pyoderma gangrenosum: a review for the gastroenterologist. Inflamm Bowel Dis 2018;24:2510-7. DOI: 10.1093/ibd/izy174
2. Kochar B, Herfarth N, Mamie C, et al. Tofacitinib for the Treatment of Pyoderma Gangrenosum. Clin Gastroenterol Hepatol 2019;17(5):991-3.
3. Gregory MH, Ciorba MA, Deepak P, et al. Successful Treatment of Pyoderma Gangrenosum with Concomitant Tofacitinib and Infliximab. Inflamm Bowel Dis 2019;25(7):e87-8. DOI: 10.1093/ibd/izz015
4. Sandborn WJ, Su C, Sands BE, et al. Tofacitinib as Induction and Maintenance Therapy for Ulcerative Colitis. N Engl J Med 2017;376(18):1723-36.
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Salmón Olavarría P, Rubio Iturria S, Nantes Castillejo Ó. Tofacitinib, a useful option for the treatment of pyoderma gangrenosum in an ulcerative colitis patient. 7977/2021


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Publication history

Received: 16/03/2021

Accepted: 26/03/2021

Online First: 13/04/2021

Published: 06/10/2021

Article revision time: 7 days

Article Online First time: 28 days

Article editing time: 204 days


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