Year 2011 / Volume 103 / Number 4
Original
Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding

pp. 196-203

José Alberto González-González, Genaro Vázquez-Elizondo, Diego García-Compeán, Juan Obed Gaytán-Torres, Ángel Ricardo Flores-Rendón, Joel Omar Jáquez-Quintana, Aldo Azael Garza-Galindo, Martha Graciela Cárdenas-Sandoval y Héctor Jesús Maldonado-Garza

Abstract
Objective: to determine the independent predictors of in-hospital death of Hispanic patients with nonvariceal upper gastrointestinal
bleeding (NVUGB).
Experimental design: prospective and observational trial.
Patients: in a period between 2000 and 2009, all patients with NVUGB admitted to our hospital were studied. Demographical and clinical characteristics, endoscopic findings and laboratory
tests were evaluated. ?² and Mann-Whitney U analyses were performed for comparisons, and binary logistic regression was employed
to identify independent predictors of in-hospital mortality.

Results: 1,067 patients were included, 65% male with a mean age of 58.8 years. Mean number of comorbidities per patient was 1.6 ± 0.76. The most frequent cause of bleeding were
gastric and duodenal ulcers (55.4%); 278 patients (25.8%) received endoscopic treatment of which 69.1% had combined therapy.

Rebleeding occurred in 36 patients (3.4%) of which 50% died. Inhospital mortality was 10.2%, of which only 3.1% was associated
to bleeding. When comparing causes of death among patients with and without comorbidities, only hypovolemic shock was found significative (48.3 vs. 25%; p = 0.020). Binary logistic regression found that the number of comorbidities, Rockall scale serum
albumin < 2.6 g/dL on admission; rebleeding and length of hospital stay were independent risk factors of in-hospital mortality.

Conclusion: the number of comorbidities, the Rockall scale score, an albumin level < 2.6 g/dL, the presence of rebleeding and hospital stay were predictors of in-hospital mortality in patients
with UNVGB.
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José Alberto González-González, Genaro Vázquez-Elizondo, Diego García-Compeán, Juan Obed Gaytán-Torres, Ángel Ricardo Flores-Rendón, Joel Omar Jáquez-Quintana, Aldo Azael Garza-Galindo, Martha Graciela Cárdenas-Sandoval y Héctor Jesús Maldonado-Garza. Predictors of in-hospital mortality in patients with non-variceal upper gastrointestinal bleeding. 196-203


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