Year 2024 / Volume 116 / Number 6
Letter
Rosai-Dorfman disease involving the entire esophagus

338-339

DOI: 10.17235/reed.2023.9753/2023

Wen-Peng Huang, Liming Li, Jianbo Gao, Lei Kang,

Abstract
We present a case of Rosai–Dorfman disease (RDD) occurred in a 6-year-old male child, characterized by extensive involvement of the esophagus. Eight months ago, the child presented with persistent fever and a diffuse dark red rash. MRI revealed a mass occupying the left nasal cavity and septal sinus and biopsy pathology confirmed the diagnosis of RDD. Following dexamethasone and prednisone treatment, the child experienced dysphagia. 18F-FDG PET/CT revealed multiple lesions with increased metabolism in the left nasal sinus, lymph nodes, widespread skin lesions, and the entire esophagus. Subsequent biopsies of lymph nodes, abdominal skin, and esophageal lesions was consistent with RDD involvement. The child is presently undergoing six cycles of VCR+Ara-c+Dex chemotherapy and the treatment is going well.
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References
[1] Elbaz Younes I, Sokol L, Zhang L. Rosai-Dorfman Disease between Proliferation and Neoplasia[J]. Cancers (Basel), 2022, 14(21):5271. DOI: 10.3390/cancers14215271.
[2] Garcia RA, DiCarlo EF. Rosai-Dorfman Disease of Bone and Soft Tissue[J]. Arch Pathol Lab Med, 2022, 146(1):40-46. DOI: 10.5858/arpa.2021-0116-RA.
[3] Catón B, Díaz de Otazu R, Aldamiz-Echebarría M, et al. [Rosai-Dorfman disease of the mesenteric lymph nodes and appendix. Secondary to salmonellosis?][J]. Rev Esp Enferm Dig, 1991, 80(4):265-267.
[4] Mahajan S, Nakajima R, Yabe M, et al. Rosai-Dorfman Disease-Utility of 18F-FDG PET/CT for Initial Evaluation and Follow-up[J]. Clin Nucl Med, 2020, 45(6):e260-e266. DOI: 10.1097/RLU.0000000000003014.
[5] Abla O, Jacobsen E, Picarsic J, et al. Consensus recommendations for the diagnosis and clinical management of Rosai-Dorfman-Destombes disease[J]. Blood, 2018, 131(26):2877-2890. DOI: 10.1182/blood-2018-03-839753.
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Huang W, Li L, Gao J, Kang L. Rosai-Dorfman disease involving the entire esophagus. 9753/2023


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Publication history

Received: 30/05/2023

Accepted: 01/06/2023

Online First: 22/06/2023

Published: 04/06/2024

Article Online First time: 23 days

Article editing time: 371 days


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