Year 2024 / Volume 116 / Number 9
Letter
Comments on: “Perianal Crohn’s disease: clinical implications, prognosis and use of resources”

510

DOI: 10.17235/reed.2023.10013/2023

Fang Cheng,

Abstract
The study by Martínez Sánchez ER et al 1 has piqued our interest as it aimed to investigate the prevalence of perianal disease, the associated phenotypical factors, its influence over prognosis and its impact in the use of health resources for patients with Crohn’s disease (CD). The authors identified that perianal disease (PD) among patients with CD is very prevalent, especially if there is rectal involvement, and entails higher healthcare costs than patients without PD due to the worse evolution at the perianal and luminal level, especially in complex forms. All of this forces us to optimize treatment strategies in these types of patients. We appreciate the authors’ hard work. And, we have a few comments on the article.
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References
1. Martínez Sánchez ER, Solá Fernández A, Pérez Palacios D, et al. Perianal Crohn's disease: clinical implications, prognosis and use of resources. Rev Esp Enferm Dig. 2022;114(5):254-258.
2. Sakha YA, Ehsani E, Roshandel E, Jalili A, Vahdani N, Hajifathali A. Assessment of the Effect of Infliximab on Immunomodulation Properties of Mesenchymal Stem Cells In Vitro. Adv Pharm Bull. 2021;11(4):739-745.
3. Cheng F, Huang Z, Li Z. Efficacy and Safety of Mesenchymal Stem Cells in Treatment of Complex Perianal Fistulas: A Meta-Analysis. Stem Cells Int. 2020;2020:8816737.
4. Huang HR, Zan H, Lin Y, Zhong YQ. Effects of azathioprine and infliximab on mesenchymal stem cells derived from the bone marrow of rats in vitro. Mol Med Rep. 2014;9(3):1005-1012.
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Cheng F. Comments on: “Perianal Crohn’s disease: clinical implications, prognosis and use of resources”. 10013/2023


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Publication history

Received: 11/10/2023

Accepted: 17/10/2023

Online First: 06/11/2023

Published: 09/09/2024

Article Online First time: 26 days

Article editing time: 334 days


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