Year 2021 / Volume 113 / Number 7
Letter
COVID-19 and the liver: the chicken or the egg dilemma

555

DOI: 10.17235/reed.2021.7861/2021

Javier Ampuero, Manuel Romero Gómez,

Abstract
After the publication of our meta-analysis, in which we demonstrated that aspartate aminotransferase (AST), alanine aminotransferase (ALT) and total bilirubin were related to a poor prognosis in patients suffering COVID-19, some authors raised the question about whether these findings are directly linked, or they are epiphenomena.
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References
Ampuero J, Sánchez-Torrijos Y, García Lozano MDR, et al. Impact of liver injury on the severity of COVID-19: Systematic Review with Meta-analysis. Rev Esp Enferm Dig. 2020 Dec 3. doi: 10.17235/reed.2020.7397/2020.
Cienfuegos J, Valenti V, Rotellar F. Hepatic injury and COVID-19: Pathogenic mechanisms or Epiphenomena? Rev Esp Enferm Dig. 2021 (in press).
Crespo J, Iglesias-García J, Hinojosa Del Val JE, et al. COVID-19 and the digestive system: protection and management during the SARS-CoV-2 pandemic. Rev Esp Enferm Dig. 2020 May;112(5):389-396.
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Ampuero J, Romero Gómez M. COVID-19 and the liver: the chicken or the egg dilemma. 7861/2021


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Publication history

Received: 03/02/2021

Accepted: 04/02/2021

Online First: 11/02/2021

Published: 07/07/2021

Article Online First time: 8 days

Article editing time: 154 days


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