Year 2020 / Volume 112 / Number 3
Letter
Rhabdomyolysis in a patient under treatment with sorafenib

243-244

DOI: 10.17235/reed.2020.6440/2019

María del Mar Díaz Alcázar, Eloísa Cervilla Sáez de Tejada, Elena Ruiz Escolano,

Abstract
We present a case of rhabdomyolysis related to treatment with sorafenib in a patient with multifocal hepatocellular carcinoma. Rhabdomyolysis is a severe situation and potentially fatal. There are no laboratory data that can predict this condition. Early diagnosis is essential for prognosis. Rhabdomyolysis has been described as an adverse reaction of several drugs but it is not frequently related to sorafenib.
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21/08/2024 4:44:30
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References
1. Hohenegger M. Drug induced rhabdomyolysis. Curr Opin Pharmacol 2012;12:335–9.
2. Tsuji K, Takemura K, Minami K, Teramoto R, Nakashima K, Yamada S, et al. A case of rhabdomyolysis related to sorafenib treatment for advanced hepatocellular carcinoma. Clin J Gastroenterol 20136:255–7.
3. Antoun S, Birdsell L, Sawyer MB, Venner P, Escudier B, Baracos VE. Association of skeletal muscle wasting with treatment with sorafenib in patients with advanced renal cell carcinoma: results from a placebo-controlled study. J Clin Oncol 2010;28(6):1054-60.
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Díaz Alcázar M, Cervilla Sáez de Tejada E, Ruiz Escolano E. Rhabdomyolysis in a patient under treatment with sorafenib. 6440/2019


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Publication history

Received: 10/06/2019

Accepted: 16/06/2019

Online First: 21/01/2020

Published: 05/03/2020

Article Online First time: 225 days

Article editing time: 269 days


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