Year 2017 / Volume 109 / Number 11
Editorial
Point of care testing for paediatric coeliac disease in the new ESPGHAN era

741-742

DOI: 10.17235/reed.2017.5337/2017

Michelle Shui Yee Lau, David S. Sanders,

Abstract
One of the challenges in coeliac disease is the significant under-diagnosis despite the increasing prevalence and international guidelines for serological screening in appropriate patient cohorts. Several point-of-care tests for coeliac disease have been developed over the past decade with the aim of improving case detection using rapid and convenient testing. Most point-of-care tests, such as Biocard, detect anti-tissue transglutaminase (tTG) IgA antibodies, whereas Simtomax uniquely detects anti-deamidated gliadin peptide (DGP) IgA/IgG antibodies. A recent head-to-head trial in adults comparing two tTG-based point-of-care tests (Biocard and Celiac Quick Test) and Simtomax found that Simtomax was superior to Biocard and Celiac Quick Test, with sensitivities of 92.7%, 72.2% and 77.8%, respectively.
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Lau M, Sanders D. Point of care testing for paediatric coeliac disease in the new ESPGHAN era. 5337/2017


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Publication history

Received: 24/10/2017

Accepted: 26/10/2017

Online First: 30/10/2017

Published: 02/11/2017

Article Online First time: 6 days

Article editing time: 9 days


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