Year 2018 / Volume 110 / Number 12
Original
Appropriateness of the use of proton pump inhibitors in the Emergency Department of a Spanish university hospital

755-761

DOI: 10.17235/reed.2018.5468/2018

Beatriz Granero-Melcon, Ignacio Morrás, Miguel Galán-DeJuana, Francisco Abad-Santos,

Abstract
Background: the use of proton pump inhibitors (PPI) has increased substantially during the last years, possibly due to a significant proportion of prescriptions that do not follow the approved indications. Objective: to assess the prevalence of PPI prescription and the appropriateness of the prescription within the Emergency Department (ED) of a Spanish university hospital. Materials and methods: a cross-sectional, retrospective prescription-indication drug-use study was performed, which selected 384 patients that presented to the ED over two days in January 2016. Results: of the total cohort, 23.2% were taking PPI before their hospital visit and only 20.2% had a correct indication and dosage; 2.9% of the patient cohort had an indication for PPI treatment but had not been prescribed them. A drug other than omeprazole was used in 25% of cases; 30.47% of the patients were discharged with a PPI and only 28.2% of them had the correct indication and dosage. Finally, 5.7% were not prescribed PPI even though it was warranted. PPI prescription increased with age whereas the indication for the prescription decreased. Furthermore, the use of these drugs was higher in hospitalized patients compared to discharged patients. Conclusions: these results are in line with similar studies, which demonstrate the existence of an over-prescription of PPI. PPI prescription needs to be improved, thereby reducing drug interactions, adverse effects and unnecessary economical expenses.
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Granero-Melcon B, Morrás I, Galán-DeJuana M, Abad-Santos F. Appropriateness of the use of proton pump inhibitors in the Emergency Department of a Spanish university hospital. 5468/2018


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Publication history

Received: 14/01/2018

Accepted: 04/10/2018

Online First: 26/10/2018

Published: 03/12/2018

Article revision time: 261 days

Article Online First time: 285 days

Article editing time: 323 days


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