Year 2017 / Volume 109 / Number 1
Letter to the Editor
Rectal neuroendocrine neoplasia: a rare tumour

79-80

DOI: 10.17235/reed.2016.4351/2016

Marina de Benito Sanz, Javier Santos Fernández, Mª Henar Núñez Rodríguez,

Abstract
Colorectal neuroendocrine tumours are rare A 78 year old man with a history of hypertension, heart disease, pacemakers, prostate adenocarcinoma.On examination for rectal bleeding, a colonoscopy was performed and at 5 cm of the anal margin a 28 mm ulcerated neoformation was found.An echo-endoscopy revealed infiltration of the muscular layer with an area of loss in the cleavage plane loss and fraying of the perirectal fat infiltration suggestive of infiltration (T3). They no lymph nodes or metastasis were identified by CAT. Radiotherapy treatment is ruled out due to having had it previously on the prostate and a proctectomy was opted for with mesorectal resection and Hartmann intervention. The pathology report revealed a large cell neuroendocrine carcinoma with numerous implants in perirectal adipose tissue and lymph metastasis in 2 lymph nodes (pT4aN1b), positive for synaptophysin, chromogranin and CD 56 with proliferation index Ki-67 50%.
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References
1. Villalonga R, Espín Basany E, López Cano M et al. Carcinomas neuroendocrinos de colon y recto: Experiencia de una unidad en seis años. Rev esp enferm dig 2008; 100:11-16.
2. Shafqat H, Ali S, Salhab M et al. Survival of patients with neuroendocrine carcinoma of the colon and rectum: a population-based analysis. Dis Colon Rectum 2015; 58(3):294-303.
3. Caplin M, Sundin A, Nillson O et al. ENETS consensus guidelines for the management of patients with digestive neuroendocrine neoplasms: Colorectal neuroendocrine neoplasms. Neuroendocrinology 2012; 95:88-97
4. Modlin IM, Lye KD, Kidd M. A 5-decade analysis of 13,715 carcinoid tumors. Cancer 2003; 97:934-59.
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Publication history

Received: 31/03/2016

Accepted: 11/04/2016

Online First: 08/11/2016

Published: 03/01/2017

Article revision time: 6 days

Article Online First time: 222 days

Article editing time: 278 days


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