Year 2023 / Volume 115 / Number 8
Letter
Weil syndrome coincident with upper gastrointestinal bleeding

458-459

DOI: 10.17235/reed.2022.9086/2022

Claudia Barber Caselles, Jesus Manuel Rivera Esteban, Alessandro Avonello Maynard, Fernando Salvador, Carmen Alonso Cotoner,

Abstract
A 48 year old male was referred to our center due to a gastrointestinal bleeding with melena secondary to a Forrest IIb gastric ulcer treated endoscopically. Physical examination revealed bilateral conjunctival suffusion, bradypsychia, and asterixis. Epidemiological history included a trip to Dominican Republic two weeks before, presenting later a flu-like syndrome. He had no history of NSAID use. Laboratory tests showed a normocytic anemia, leukocytosis with neutrophilia, acute renal failure, severe hyponatremia, a predominant direct hyperbilirubinemia, hyperamylasemia, and mild coagulopathy (Table 1). An abdominal ultrasound was performed, with no pathological findings, and a chest-abdominal computed tomography (CT), bilateral diffuse ground glass pulmonary opacities and pleural effusion, mild hepatomegaly, and peritoneal and gastrohepatic ligament lymphadenopathy, with no signs of acute pancreatitis. A second look upper endoscopy revealed a Forrest III gastric ulcer. Gastric biopsies results ruled out malignancy and Helicobacter pylori infection. Due to his recent travel history combined with his characteristic signs and symptoms a clinical diagnosis of leptospirosis was made and empirical antibiotic therapy with meropenem was started. The serology for Leptospira was positive (IgG 1/1600) and antibiotic therapy was de-escalated to ceftriaxone with clinical and analytical remission on day five of his hospital stay with complete radiological resolution at 6 months.
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References
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Barber Caselles C, Rivera Esteban J, Maynard A, Salvador F, Alonso Cotoner C. Weil syndrome coincident with upper gastrointestinal bleeding. 9086/2022


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Publication history

Received: 17/07/2022

Accepted: 26/09/2022

Online First: 20/10/2022

Published: 26/07/2023

Article Online First time: 95 days

Article editing time: 374 days


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