Year 2023 / Volume 115 / Number 4
Letter
Colonic perineurioma of the transverse colon: presentation of a rare neoplasm in an atypical location

221

DOI: 10.17235/reed.2023.9440/2022

Emanuel Dias, Marco Antonio Silva, João Carlos Almeida, Jorge Pinheiro, Guilherme Macedo,

Abstract
A 51-year-old male with previous medical history of dyslipidemia performed screening colonoscopy, which revealed a sessile polypoid lesion with a diameter of approximately 8 mm located at the proximal transverse colon, which was resected en bloc with a cold snare. Remarkably, histopathological examination revealed a proliferation of spindle cells in the lamina propria entrapping colonic crypts without evidence of nuclear pleomorphism, mitotic figures or necrosis. On immunohistochemistry, spindle cells were diffusely positive for glucose transporter-1 and negative for S100, DOG1, CD34 and smooth muscle actin. These features were consistent with a diagnosis of colonic perineurioma.
Share Button
New comment
Comments
No comments for this article
References
1. Eslami-Varzaneh F, Washington K, Robert ME, Kashgarian M, Goldblum JR, Jain D. Benign fibroblastic polyps of the colon: a histologic, immunohistochemical, and ultrastructural study. Am J Surg Pathol. 2004;28:374–8.
2. Kamionkowski S, Issak A, Zhang C, Wang Y, Kyprianou A. A solitary sigmoid perineurioma in an otherwise healthy 30-Year-Old male. Cureus. 2021;13(5):e15104.
3. van Wyk AC, van Zyl H, Rigby J. Colonic perineurioma (benign fibroblastic polyp): case report and review of the literature. Diagn Pathol. 2018;13(1):16.
4. McCarthy AJ, Karamchandani DM, Chetty R. Neural and neurogenic tumours of the gastroenteropancreaticobiliary tract. Journal of Clinical Pathology. 2018;71:565-578.
5. García IC, Romero IL, Prián RMM, Morillas DR. Importance of immunohistochemistry in the differential diagnosis of gastric stromal tumors: GIST vs. schwannoma. Rev Esp Enferm Dig. 2022;114(5):305-306.
Related articles

Letter

A granular cell tumor: an unusual colon polyp

DOI: 10.17235/reed.2018.5918/2018

Citation tools
Dias E, Silva M, Almeida J, Pinheiro J, Macedo G. Colonic perineurioma of the transverse colon: presentation of a rare neoplasm in an atypical location. 9440/2022


Download to a citation manager

Download the citation for this article by clicking on one of the following citation managers:

Metrics
This article has received 914 visits.
This article has been downloaded 52 times.

Statistics from Dimensions


Statistics from Plum Analytics

Publication history

Received: 23/12/2022

Accepted: 01/01/2023

Online First: 16/01/2023

Published: 03/04/2023

Article Online First time: 24 days

Article editing time: 101 days


Share
This article hasn't been rated yet.
Reader rating:
Valora este artículo:




Asociación Española de Ecografía Digestiva Sociedad Española de Endoscopia Digestiva Sociedad Española de Patología Digestiva
The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva
Cookie policy Privacy Policy Legal Notice © Copyright 2023 y Creative Commons. The Spanish Journal of Gastroenterology